Serosurvey For Measles, Mumps and Rubella in Children and Adolescents with Chronic Kidney Disease

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dc.contributor.authorA, Meyyanen_US
dc.contributor.authorTyagi, Vernikaen_US
dc.contributor.authorDabas, Aashimaen_US
dc.contributor.authorMantan, Muktaen_US
dc.contributor.authorManchanda, Vikasen_US
dc.date.accessioned2025-08-13T09:09:42Z
dc.date.available2025-08-13T09:09:42Z
dc.date.issued2025-01
dc.description.abstractOBJECTIVES Children with Chronic Kidney Disease (CKD) are at increased risk for vaccine-preventable diseases. The primary objec?ve of the study was to es?mate IgG an?body ?ters against measles, mumps, and rubella (MMR) in children with CKD and healthy controls who were previously immunized with measles/ MMR vaccine. METHODS This case control study was conducted between January 2019 and January 2020. Children aged 2-18 years with CKD and healthy controls who had received at least one dose of measles/MMR were included. Children on dialysis were excluded. Clinical details of immuniza?on were recorded, and an?body ?ters measured by ELISA based kits. RESULTS 120 children (60 cases and 60 controls) were enrolled; seroprotec?on rates for measles, mumps and rubella in the CKD group and control group were 90% vs 86.7%, P = 0.01; 71.7% vs 77.7%, P = 0.77; and 86.7% vs 88.3%; P = 0.05, respec?vely, with lower an?body ?ters for mumps and measles in late-stages (stage 4 or 5) CKD. CONCLUSIONS Seroprotec?on amongst children with CKD for measles, rubella and mumps is not inferior to that in controls. However, children with late- stage CKD (stages 4 and 5) have lower seroprotec?on especially for mumps and measles compared to those with early-stage (1-3) CKD.en_US
dc.identifier.affiliationsDepartments of Pediatrics, Maulana Azad Medical College, New Delhi, Indiaen_US
dc.identifier.affiliationsDepartments of Pediatrics, Maulana Azad Medical College, New Delhi, Indiaen_US
dc.identifier.affiliationsDepartments of Pediatrics, Maulana Azad Medical College, New Delhi, Indiaen_US
dc.identifier.affiliationsDepartments of Pediatrics, Maulana Azad Medical College, New Delhi, Indiaen_US
dc.identifier.affiliationsMicrobiology, Maulana Azad Medical College, New Delhi, Indiaen_US
dc.identifier.citationA Meyyan, Tyagi Vernika, Dabas Aashima, Mantan Mukta, Manchanda Vikas . Serosurvey For Measles, Mumps and Rubella in Children and Adolescents with Chronic Kidney Disease. Indian Pediatrics. 2025 Jan; 62(1): 49-52en_US
dc.identifier.issn0019-6061
dc.identifier.issn0974-7559
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/251355
dc.languageenen_US
dc.publisherIndian Academy of Pediatricsen_US
dc.relation.issuenumber1en_US
dc.relation.volume62en_US
dc.source.urihttps://indianpediatrics.net/jan2025/49.pdfen_US
dc.subjectAntibodyen_US
dc.subjectImmunityen_US
dc.subjectRenalen_US
dc.subjectVaccine-preventable disease.en_US
dc.titleSerosurvey For Measles, Mumps and Rubella in Children and Adolescents with Chronic Kidney Diseaseen_US
dc.typeJournal Articleen_US
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