The effect of tetanus toxoid in leprosy patients.

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dc.contributor.authorShwe, Ten_US
dc.contributor.authorThaung, Uen_US
dc.contributor.authorToe, Men_US
dc.contributor.authorMya, M Men_US
dc.contributor.authorMyint, Ten_US
dc.date.accessioned1990-01-01en_US
dc.date.accessioned2009-05-28T10:02:06Z
dc.date.available1990-01-01en_US
dc.date.available2009-05-28T10:02:06Z
dc.date.issued1990-01-01en_US
dc.description.abstractSince cases of lepra reaction following smallpox vaccination and BCG vaccination had been reported the effect of tetanus immunisation on leprosy patients (whether it may provoke a lepra reaction or not) was studied. Three doses of purified tetanus toxoid (one ml initially, one ml after six weeks and one ml after six months) were given to 357 leprosy patients and 60 patients living in the same environ were followed as controls. The antibody response following immunisation was followed in six lepromatous leprosy patients using toxin antitoxin neutralisation test at the Lf/1000 level in mice and in three of them the antibody titre of leprosy patients rose to satisfactory level. The number of lepra reactions in these patients was monitored for nine months (two months before vaccination, during the six months period of vaccination and one month after the last dose of vaccine). There was no significant rise in the number of patients with reaction following the vaccination.en_US
dc.description.affiliationDepartment of Medical Research Ministry of Health, Rangoon, Burma.en_US
dc.identifier.citationShwe T, Thaung U, Toe M, Mya MM, Myint T. The effect of tetanus toxoid in leprosy patients. Indian Journal of Leprosy. 1990 Jan-Mar; 62(1): 104-8en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/54754
dc.language.isoengen_US
dc.subject.meshAntibodies, Bacterial --biosynthesisen_US
dc.subject.meshErythema Nodosum --immunologyen_US
dc.subject.meshHumansen_US
dc.subject.meshLeprosy --immunologyen_US
dc.subject.meshLeprosy, Lepromatous --immunologyen_US
dc.subject.meshTetanus Toxoid --immunologyen_US
dc.titleThe effect of tetanus toxoid in leprosy patients.en_US
dc.typeJournal Articleen_US
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