Immunological status of patients in carcinoma head and neck.

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dc.contributor.authorVasenwala, S Men_US
dc.contributor.authorAziz, Men_US
dc.contributor.authorRattan, Aen_US
dc.contributor.authorAhmad, K Nen_US
dc.date.accessioned2009-05-28T06:32:02Z
dc.date.available2009-05-28T06:32:02Z
dc.date.issued1989-09-01en_US
dc.description.abstractThe cell mediated immune response in 45 patients of cancer, head and neck was evaluated by various parameters and compared with 20 control cases. (DNCB) Dinitrochlorobenzene cutaneous reactivity in vivo was compared with T lymphocytes, estimated as active rosette forming cells (ARFC) and Total rosette forming cells (TRFC) in peripheral blood. The ratio of TRFC/ARFC was studied in various histological subtypes of cancer head and neck. Lymphocytic infiltration around tumor mass was correlated with peripheral blood lymphocyte (PBL), ARFC and TRFC levels in blood. Significant difference was noted in the level of peripheral blood lymphocytes (PBL). TRFC and ARFC between control cases and cancer patients. There was a marked increase in all three parameters i.e. PBL, TRFC, ARFC (P less than 0.001) and a positive DNCB reaction in Adenocarcinoma of nasopharynx, thyroid and salivary gland and a significant decrease in Squamous cell Carcinoma of oral cavity and larynx (p less than 0.001) associated with impaired DNCB sensitivity. These parameters serve as an assessment of the degree of immune reactivity of the host to the malignant tumours.en_US
dc.identifier.citationVasenwala SM, Aziz M, Rattan A, Ahmad KN. Immunological status of patients in carcinoma head and neck. Indian Journal of Cancer. 1989 Sep; 26(3): 137-44en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/49986
dc.language.isoengen_US
dc.source.urihttps://www.indianjcancer.comen_US
dc.subject.meshAdenocarcinoma --immunologyen_US
dc.subject.meshAdolescenten_US
dc.subject.meshAdulten_US
dc.subject.meshAgeden_US
dc.subject.meshAged, 80 and overen_US
dc.subject.meshCarcinoma, Squamous Cell --immunologyen_US
dc.subject.meshFemaleen_US
dc.subject.meshHead and Neck Neoplasms --immunologyen_US
dc.subject.meshHumansen_US
dc.subject.meshImmunity, Cellularen_US
dc.subject.meshLymphocytes --immunologyen_US
dc.subject.meshMaleen_US
dc.subject.meshMiddle Ageden_US
dc.subject.meshRosette Formationen_US
dc.subject.meshSkin Testsen_US
dc.titleImmunological status of patients in carcinoma head and neck.en_US
dc.typeJournal Articleen_US
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