Two routes of administration of mitomycin C in a trabeculectomy

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dc.contributor.authorPillai, Manjuen_US
dc.contributor.authorKalegore, Aniket Aen_US
dc.contributor.authorMathews, Ann Meryen_US
dc.contributor.authorKrishnadas, SRen_US
dc.date.accessioned2023-08-25T06:32:06Z
dc.date.available2023-08-25T06:32:06Z
dc.date.issued2022-02
dc.description.abstractBackground: The introduction of mitomycin C (MMC) as an adjunct to trabeculectomy was a major advance in the ability to improve the Intra ocular pressure lowering efficiency of the procedure. The time tested traditional way of administration of MMC is via a sponges soaked in it, duration and concentration varies depending on risk of failure. A subconjunctival injection of MMC instead of these sponges is recently being used as a promising alternative. Purpose: Here is the video demonstrating the 2 possible ways to prepare and apply MMC during a trabeculectomy surgery. Synopsis: Intraoperative injection of MMC in trabeculectomy has several advantages over conventional method ofsponge application. A large MMC treatment area produces more diffuse and elevated blebs. Large?area MMC application also seems to increase long?term success without increasing the complication rates in trabeculectomies. Direct and diffuse application of MMC by injection may promote less scarring and vascularization of the bleb. To achieve the same surface area of exposure with sponges, i.e.achieved with injection, the surgeon must use multiple sponges, all of which must be carefully collected thereafter. The injection method,therefore,eliminates the risk of retained sponges. Highlights: injection of MMC may be as safe and as effective as conventional sponge application of MMC with comparable estimated complete treatment success with relatively lower complication ratesen_US
dc.identifier.affiliationsAravind Eye Hospital, Glaucoma Department, Madurai, Tamil Nadu, Indiaen_US
dc.identifier.citationPillai Manju, Kalegore Aniket A, Mathews Ann Mery, Krishnadas SR. Two routes of administration of mitomycin C in a trabeculectomy. Indian Journal of Ophthalmology. 2022 Feb; 70(2): 673-674en_US
dc.identifier.issn1998-3689
dc.identifier.issn0301-4738
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/224172
dc.languageenen_US
dc.publisherAll India Ophthalmological Societyen_US
dc.relation.issuenumber2en_US
dc.relation.volume70en_US
dc.source.urihttps://doi.org/10.4103/ijo.IJO_1889_22en_US
dc.subjectInjectable mitomycin Cen_US
dc.subjectsponge?soaked mitomycin Cen_US
dc.subjecttrabeculectomyen_US
dc.titleTwo routes of administration of mitomycin C in a trabeculectomyen_US
dc.typeJournal Articleen_US
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