Effect of Papain Urea versus EUSOL in Diabetic Foot Ulcer Management
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Date
2024-10
Journal Title
Journal ISSN
Volume Title
Publisher
THE INDIAN MEDICAL ASSOCIATION
Abstract
Background : Cases of Diabetes Mellitus (DM) are increasing day by day with a perpetual increase in diabetic foot ulcer among these patients. Most of the patients present with infected ulcers with slough and unhealthy tissue. Surgical debridement needed as a initial line of management and later slough removal by chemical debridement agents. In our study we compared the effectiveness of chemical wound debridement using papain urea dressing as against Edinburgh University Solution of Lime (EUSOL) in diabetic foot ulcer. Also we tried to study the associated risk factors involved in the outcome of an ulcer. Materials and Methods : Patients diagnosed with Type 2 Diabetes Mellitus with a foot ulcer classified under Wagner’s classification I and II were taken up for the study. They were randomly allocated into two groups of 51 members each. EUSOL was used in one group and Papain Urea in the other groups as dressing agent.The rate of healing and other factors related to the foot ulcer were compared between the two groups. Results : It was observed that there was significant reduction in ulcer size and slough in ulcers where Papain Urea was used as dressing agent. There was also better and faster granulation tissue formation among the group of patients using Papain Urea as dressing agent. The observation was made by measuring the surface area of slough and granulation tissue. Conclusions : In diabetic foot ulcer, Wagner’s classification I and II Papain Urea dressings showed significant reduction in the duration of healing time and faster slough removal. It also helped in forming healthy granulation tissue, without any associated complications. Hence, Papain Urea dressings can be considered as a good option for chemical debridement and wound healing for diabetic foot ulcer.
Description
Keywords
Papain urea, EUSOL, Diabetic foot ulcer, Diabetes Mellitus, Slough
Citation
Rajkumar Sharath, Philip Achu Jacob, Rajkumar Sathish, C L Rahul Raj, Chand Ashwin, C S Umaakanth Soundar . Effect of Papain Urea versus EUSOL in Diabetic Foot Ulcer Management. Journal of the Indian Medical Association. 2024 Oct; 122(10): 64-69