Nanostructure-based platforms-current prospective in ophthalmic drug delivery.
| dc.contributor.author | Sharma, Rakesh Kumar | |
| dc.contributor.author | Yassin, Alaa Eldeen B | |
| dc.date.accessioned | 2015-02-02T08:52:41Z | |
| dc.date.available | 2015-02-02T08:52:41Z | |
| dc.date.issued | 2014-07 | |
| dc.description.abstract | The topically applied drugs as drops are washed off from the eye in very short period, resulting in low ocular bioavailability of drugs. Number of approaches have been attempted to increase the bioavailability and the duration of action of ocular drugs. This review provides an insight into various novel approaches; hydrophilic nanogels, solid lipid nanoparticles, and nanosponges applied very recently in the delivery of insoluble drugs, prolonging the ocular residence time, minimize pre‑corneal drug loss and, therefore, bioavailability and therapeutic efficacy of the drugs. Despite various scientific approaches, efficient ocular drug delivery remains a challenge for pharmaceutical scientists. | en_US |
| dc.identifier.citation | Sharma Rakesh Kumar, Yassin Alaa Eldeen B. Nanostructure-based platforms-current prospective in ophthalmic drug delivery. Indian Journal of Ophthalmology. 2014 July ; 62 (7): 768-772. | en_US |
| dc.identifier.uri | https://imsear.searo.who.int/handle/123456789/155698 | |
| dc.language.iso | en | en_US |
| dc.source.uri | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4152643/ | en_US |
| dc.subject | Hydrophillic nanogels | en_US |
| dc.subject | ophthalmic drug delivery | en_US |
| dc.subject | nanosponges | en_US |
| dc.subject | solid lipid nanoparticles | en_US |
| dc.title | Nanostructure-based platforms-current prospective in ophthalmic drug delivery. | en_US |
| dc.type | Article | en_US |