Observations on hepatic structure and function in fibro-calculous pancreatic diabetes (FCPD) vis-a-vis other diabetic subtypes.

Simple item page
dc.contributor.authorChattopadhyay, P Sen_US
dc.contributor.authorChattopadhyay, Ren_US
dc.contributor.authorGoswami, Ren_US
dc.contributor.authorGupta, S Ken_US
dc.date.accessioned1998-04-22en_US
dc.date.accessioned2009-05-29T12:30:23Z
dc.date.available1998-04-22en_US
dc.date.available2009-05-29T12:30:23Z
dc.date.issued1998-04-22en_US
dc.description.abstractInvestigations of liver function and histology were undertaken in thirty four patients with Fibrocalculous Pancreatic Diabetes (FCPD). The data obtained were compared with those of similarly aged members of a diabetic control group comprising twelve patients with Protein Deficient Diabetes Mellitus (PDDM), twelve with Type 1 diabetes or Insulin Dependent Diabetes Mellitus (IDDM) and four young patients with Type 2 Diabetes of Non-Insulin Dependent Diabetes Mellitus (NIDDM). None of them had apparent past or present liver disease. Elevations of serum ALT (SGPT) and alkaline phosphatase levels were fairly common and was often associated with mild fatty changes and occasionally with focal necrosis and inflammatory changes. Cirrhosis and inflammatory changes per se were infrequent and fatty changes per se did not occur. In contrast patients belonging to the other diabetic subsets were very occasionally afflicted with hepatic abnormalities or not afflicted at all. We propose that loss of hepatotrophic actions mediated by insulin and glucagon could initiate and/or enhance hepatic abnormalities in FCPD where deficiencies of insulin and glucagon coexist.en_US
dc.description.affiliationDepartment of Nutrition and Metabolic Diseases, School of Tropical Medicine, Calcutta.en_US
dc.identifier.citationChattopadhyay PS, Chattopadhyay R, Goswami R, Gupta SK. Observations on hepatic structure and function in fibro-calculous pancreatic diabetes (FCPD) vis-a-vis other diabetic subtypes. Indian Journal of Pathology & Microbiology. 1998 Apr; 41(2): 141-6en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/74663
dc.language.isoengen_US
dc.source.urihttps://www.ijpmonline.orgen_US
dc.subject.meshAdolescenten_US
dc.subject.meshAdulten_US
dc.subject.meshAlanine Transaminase --blooden_US
dc.subject.meshAlkaline Phosphatase --blooden_US
dc.subject.meshCalculi --pathologyen_US
dc.subject.meshChilden_US
dc.subject.meshChronic Diseaseen_US
dc.subject.meshDiabetes Mellitus --physiopathologyen_US
dc.subject.meshFatty Liver --pathologyen_US
dc.subject.meshFemaleen_US
dc.subject.meshHumansen_US
dc.subject.meshLiver --enzymologyen_US
dc.subject.meshLiver Cirrhosis --pathologyen_US
dc.subject.meshMaleen_US
dc.subject.meshPancreatitis --pathologyen_US
dc.titleObservations on hepatic structure and function in fibro-calculous pancreatic diabetes (FCPD) vis-a-vis other diabetic subtypes.en_US
dc.typeComparative Studyen_US
dc.typeJournal Articleen_US
Files
License bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
license.txt
Size:
1.79 KB
Format:
Plain Text
Description:
Download
Collections
Indian Journal of Pathology & Microbiology