Rapidly progressive IgA nephropathy.
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2005-03-07
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Abstract
A 14-year-old boy presented with macroscopic hematuria and a rapid deterioration in renal function. Percutaneous renal biopsy demonstrated severe crescentic IgA nephropathy (IgAN) with extensive (88%) glomerular crescent formation. After started intravenous administration of high-dose pulse methylprednisolone, severe nausea and general malaise accompanied by a rapid increase in Blood Urea Nitrogen (BUN) and serum creatinine levels appeared, however, the renal function ameliorated rapidly and fully recovered by following oral administration of corticosteroid. The clinical presentation of our case seems to be very remarkable compared to previously reported cases of rapidly progressive IgAN.
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Kobayashi N, Nishida M, Aoyama M, Yokoi K, Yahata T, Tatsujiro T, Sakata K, Shiraishi I, Itoi T, Hamaoka K. Rapidly progressive IgA nephropathy. Indian Journal of Pediatrics. 2005 Mar; 72(3): 257-60