Thyroid stimulating hormone receptor antibody in thyroid diseases.

Simple item page
dc.contributor.authorVadivelu, Nen_US
dc.contributor.authorStephen, D Cen_US
dc.contributor.authorKanagasabapathy, A Sen_US
dc.contributor.authorSeshadri, M Sen_US
dc.date.accessioned1990-08-01en_US
dc.date.accessioned2009-05-27T07:34:47Z
dc.date.available1990-08-01en_US
dc.date.available2009-05-27T07:34:47Z
dc.date.issued1990-08-01en_US
dc.description.abstractThyroid stimulating hormone receptor antibody (TRA) was estimated as a measure of TSH binding inhibitory immunoglobulin (TBII) in 48 persons. These included (i) 14 controls; (ii) 23 patients with Graves' disease who were tested for TRA within 3 months of commencing treatment with carbimazole of which 13 were studied serially; (iii) 5 patients with toxic nodular goitre; (iv) 4 with euthyroid exophthalmos; and (v) 2 neonates of thyrotoxic mothers. TRA was measured with an RIA system, while total thyroxine (T4), free thyroxine concentration (FTC) and TSH were also estimated along with TRA. All controls showed undetectable TRA levels; 87 per cent of patients with Graves' disease were TRA positive within 3 months of starting carbimazole therapy. In the serial study, 5 patients with Graves' disease who had undetectable TRA initially remained so while on treatment. Seven out of the remaining 8 patients showed a decline of TRA levels to normal over 3 to 18 months. This decline coincided with clinical and biochemical recovery.en_US
dc.description.affiliationDepartment of Clinical Biochemistry, Christian Medical College & Hospital, Vellore.en_US
dc.identifier.citationVadivelu N, Stephen DC, Kanagasabapathy AS, Seshadri MS. Thyroid stimulating hormone receptor antibody in thyroid diseases. Indian Journal of Medical Research. 1990 Aug; 92(): 220-3en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/21263
dc.language.isoengen_US
dc.source.urihttps://icmr.nic.in/ijmr/ijmr.htmen_US
dc.subject.meshAdulten_US
dc.subject.meshAgeden_US
dc.subject.meshAntibodies --analysisen_US
dc.subject.meshAutoantibodies --analysisen_US
dc.subject.meshCarbimazole --therapeutic useen_US
dc.subject.meshFemaleen_US
dc.subject.meshHumansen_US
dc.subject.meshImmunoglobulins, Thyroid-Stimulatingen_US
dc.subject.meshMaleen_US
dc.subject.meshMiddle Ageden_US
dc.subject.meshReceptors, Thyrotropin --analysisen_US
dc.subject.meshThyroid Diseases --drug therapyen_US
dc.subject.meshThyroid Gland --immunologyen_US
dc.titleThyroid stimulating hormone receptor antibody in thyroid diseases.en_US
dc.typeJournal Articleen_US
dc.typeResearch Support, Non-U.S. Gov'ten_US
Files
License bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
license.txt
Size:
1.79 KB
Format:
Plain Text
Description:
Download
Collections
Indian Journal of Medical Research