Prevalence of Hepatitis C Virus in Oral Lichen Planus and the Levels of Aminotransferase Hepatic Enzymes in Patients with Oral Lichen Planus

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dc.contributor.authorMalik, Imranen_US
dc.contributor.authorJangam, Daya Ken_US
dc.contributor.authorAhmed, Aniesen_US
dc.contributor.authorMir, Faheem Muzaffaren_US
dc.contributor.authorKaur, Jasdeepen_US
dc.contributor.authorAnjum, Gulnaazen_US
dc.date.accessioned2019-12-06T09:25:54Z
dc.date.available2019-12-06T09:25:54Z
dc.date.issued2018-03
dc.description.abstractBackground: Oral lichen planus (OLP) is a relatively common skin and oral disease that manifests as a mucous reaction to a variety of etiologic factors, including autoimmune disease, drug reaction, diabetes mellitus (DM), hypertension, hepatitis C virus (HCV), urolithiasis, psychogenic factors, and bacterial infection. It is one of the most frequent oral lesion found in patients with hepatitis C virus (HCV) infection. Objective: The purpose of this study was to investigate the relationship between HCV infection and OLP as there is a high prevalence of HCV infection in India, and to assess the levels of aminotransferase enzymes (SGPT/SGOT) in patients with OLP. Methods: The study consisted of 25 histopathologically confirmed patients of OLP and 25 subjects with age and sex matched healthy volunteers visiting the outpatient department of a dental hospital over a period of 1 year. All subjects in both groups were subjected to serum glutamic oxaloacetic transaminase (SGOT), serum glutamic pyruvic transaminase (SGPT) and HCV antibodies detection. Results: The average HCV antibody between study and control group was statistically nonsignificant with p=0.965. The percentage of patients with elevated SGOT and SGPT values was higher among the OLP patients in the study group ((32.0%) i.e. >45 IU/L) in comparison to subjects in the control group (0%). Hence, SGOT and SGPT value was statistically significant (p value= 0.002). Conclusion: OLP in certain populations can be used as a marker for HCV infection in addition to transaminase hepatic enzymes level.en_US
dc.identifier.affiliationsMDS, Community Health Center Kandi, J&K Govt. Health Dept.en_US
dc.identifier.affiliationsProf & HOD Deptt of Oral Medicine & Radiology, Sinhgad Dental College & Hospital Pune. MDS, Dj College of Dental Sciences & Rseacrch Modinagar Delhi/NCR.en_US
dc.identifier.affiliationsMDS, Lecturer, Dept. of Biomedical Dental Sciences, University Of Dammam College Of Dentistry, Saudi Arabia.en_US
dc.identifier.affiliationsMDS, Senior Lecturer, Oral Medicine & Radiology, Shaheed Kartar ingh Sarabha Dental College, Sarabha.en_US
dc.identifier.affiliationsPG Student, AME'S Dental College, Raichur Karnataka.en_US
dc.identifier.citationMalik Imran, Jangam Daya K, Ahmed Anies, Mir Faheem Muzaffar, Kaur Jasdeep, Anjum Gulnaaz. Prevalence of Hepatitis C Virus in Oral Lichen Planus and the Levels of Aminotransferase Hepatic Enzymes in Patients with Oral Lichen Planus. Annals of International medical and Dental Research. 2018 Mar; 4(2): 73-77en_US
dc.identifier.issn2395-2822
dc.identifier.issn2395-2814
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/188481
dc.languageenen_US
dc.publisherSociety for Health Care & Research Developmenten_US
dc.relation.issuenumber2en_US
dc.relation.volume4en_US
dc.source.urihttps://doi.org/10.21276/aimdr.2018.4.2.DE16en_US
dc.titlePrevalence of Hepatitis C Virus in Oral Lichen Planus and the Levels of Aminotransferase Hepatic Enzymes in Patients with Oral Lichen Planusen_US
dc.typeJournal Articleen_US
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