Methotrexate Induced Stevens Johnson Syndrome: A Rare Case Report

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dc.contributor.authorArora, Surabhien_US
dc.contributor.authorAbidi, Afrozen_US
dc.contributor.authorFatima, Farihaen_US
dc.contributor.authorHasan, Roohanaen_US
dc.contributor.authorRizvi, Darakhshanen_US
dc.contributor.authorThadani, Anupriyaen_US
dc.date.accessioned2019-11-16T07:21:37Z
dc.date.available2019-11-16T07:21:37Z
dc.date.issued2019-01
dc.description.abstractMethotrexate (MTX) is a folic acid antagonist with cytotoxic and immunosuppressant activity andwith potent antirheumatic action. It is commonly a first choice Disease modifying antirheumatic drug (DMARD). There were some spurious reports of Adverse Drug Reaction (ADR) by this drug. Here we report a rare occurrence of Stevens-Johnson syndrome (SJS) / Toxic Epidermal Necrolysis (TEN) after the use of Methotrexate. Naranjo score for this adverse drug event was six, thereby making it a probable ADR. Symptomatic management of the patient was done and the offending drug was withdrawn. We are presenting this case to highlight the serious adverse reactions possible from a routinely prescribeddrugen_US
dc.identifier.affiliationsDepartment of Pharmacology, Era's Lucknow Medical College & Hospital, Sarfarazganj Lucknow, U.P., India-226003en_US
dc.identifier.citationArora Surabhi, Abidi Afroz, Fatima Fariha, Hasan Roohana, Rizvi Darakhshan, Thadani Anupriya. Methotrexate Induced Stevens Johnson Syndrome: A Rare Case Report. Era's Journal of Medical Research. 2019 Jan-Jun; 5(2): 194-196en_US
dc.identifier.issn2348-9839
dc.identifier.issn2394-5222
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/184015
dc.languageenen_US
dc.publisherEra's Lucknow Medical College and Hospitalen_US
dc.relation.issuenumber2en_US
dc.relation.volume5en_US
dc.subjectMethotrexateen_US
dc.subjectStevens-Johnson syndromeen_US
dc.subjectRheumatoid arthritisen_US
dc.subjectAdverse Drug Reactionen_US
dc.titleMethotrexate Induced Stevens Johnson Syndrome: A Rare Case Reporten_US
dc.typeJournal Articleen_US
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