Development of insulin delivery systems.

Simple item page
dc.contributor.authorSiddiqui, N Ien_US
dc.contributor.authorSiddiqui, Nien_US
dc.contributor.authorRahman, Sen_US
dc.contributor.authorNessa, Aen_US
dc.date.accessioned2008-01-21en_US
dc.date.accessioned2009-05-27T03:52:53Z
dc.date.available2008-01-21en_US
dc.date.available2009-05-27T03:52:53Z
dc.date.issued2008-01-21en_US
dc.descriptionMymensingh Medical Journal. 52 references.en_US
dc.description.abstractDelivery system of insulin is vital for its acceptance and adherence to therapy for achieving the glycemic targets. Enormous developments have occurred in the delivery system of insulin during the last twenty years and each improvement was aimed at two common goals: patients convenience and better glycemic control. Till to date, the various insulin delivery systems are: syringes/vials, injection aids, jet injectors, transmucosal delivery, transdermal delivery, external insulin infusion pump, implantable insulin pumps, insulin pens and insulin inhalers. Syringe/vial is the oldest and conventional method, still widely used and relatively cheaper. Modern plastic syringes are disposable, light weight with microfine needle for patients convenience and comfort. Oral route could be the most acceptable and viable, if the barriers can be overcome and under extensive trial. Insulin pen device is an important milestone in the delivery system of insulin as it is convenient, discrete, painless, attractive, portable with flexible life style and improved quality of life. More than 80% of European diabetic patients are using insulin pen. Future digital pen will have better memory option, blood glucose monitoring system, insulin dose calculator etc. Insulin infusion pump is a good option for the children, busy patients with flexible lifestyle and those who want to avoid multiple daily injections. Pulmonary route of insulin delivery is a promising, effective, non-invasive and acceptable alternative method. Exubera, the world first insulin inhaler was approved by FDA in 28 January 2006. But due to certain limitations, it has been withdrawn from the market in October 2007. The main concern of inhaled insulin are: long term pulmonary safety issues, cost effectiveness and user friendly device. In future, more acceptable and cost effective insulin inhaler will be introduced. Newer avenues are under extensive trial for better future insulin delivery systems.en_US
dc.description.affiliationDepartment of Endocrinology, Mymensingh Medical College, Mymensingh & Editor, Mymensingh Medical Journal, Mymensingh, Bangladesh. mnisendo@yahoo.comen_US
dc.identifier.citationSiddiqui NI, Siddiqui N, Rahman S, Nessa A. Development of insulin delivery systems. Mymensingh Medical Journal. 2008 Jan; 17(1): 102-10en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/1171
dc.language.isoengen_US
dc.subject.meshDrug Delivery Systemsen_US
dc.subject.meshEquipment Designen_US
dc.subject.meshHumansen_US
dc.subject.meshHypoglycemic Agents --administration & dosageen_US
dc.subject.meshInsulin --administration & dosageen_US
dc.titleDevelopment of insulin delivery systems.en_US
dc.typeJournal Articleen_US
dc.typeReviewen_US
Files
License bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
license.txt
Size:
1.79 KB
Format:
Plain Text
Description:
Download
Collections
Mymensingh Medical Journal