Dynamical complexity and temporal plasticity in pancreatic beta-cells.

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dc.contributor.authorBertram, Ren_US
dc.contributor.authorSherman, Aen_US
dc.date.accessioned2000-06-06en_US
dc.date.accessioned2009-06-01T14:40:37Z
dc.date.available2000-06-06en_US
dc.date.available2009-06-01T14:40:37Z
dc.date.issued2000-06-06en_US
dc.description58 references.en_US
dc.description.abstractWe discuss some of the biological and mathematical issues involved in understanding and modelling the bursting electrical activity in pancreatic beta-cells. These issues include single-cell versus islet behaviour, parameter heterogeneity, channel noise, the effects of hormones, neurotransmitters, and ions, and multiple slow biophysical processes. Some of the key experimental and modelling studies are described, and some of the major open questions are discussed.en_US
dc.description.affiliationInstitute of Molecular Biophysics, Florida State University, Tallahassee, FL 32306, USA. bertram@sb.fsu.eduen_US
dc.identifier.citationBertram R, Sherman A. Dynamical complexity and temporal plasticity in pancreatic beta-cells. Journal of Biosciences. 2000 Jun; 25(2): 197-209en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/110996
dc.language.isoengen_US
dc.source.urihttps://www.ias.ac.in/jbiosci/index.htmlen_US
dc.subject.meshAcetylcholine --pharmacologyen_US
dc.subject.meshAnimalsen_US
dc.subject.meshBiological Clocksen_US
dc.subject.meshCalcium --pharmacologyen_US
dc.subject.meshCell Communicationen_US
dc.subject.meshCell Separationen_US
dc.subject.meshElectrophysiologyen_US
dc.subject.meshGlucose --pharmacologyen_US
dc.subject.meshHumansen_US
dc.subject.meshIon Channels --metabolismen_US
dc.subject.meshIslets of Langerhans --physiologyen_US
dc.subject.meshModels, Biologicalen_US
dc.subject.meshNonlinear Dynamicsen_US
dc.titleDynamical complexity and temporal plasticity in pancreatic beta-cells.en_US
dc.typeJournal Articleen_US
dc.typeResearch Support, U.S. Gov't, Non-P.H.S.en_US
dc.typeReviewen_US
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