A randomized comparison of ginger and dimenhydrinate in the treatment of nausea and vomiting in pregnancy.

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dc.contributor.authorPongrojpaw, Densaken_US
dc.contributor.authorSomprasit, Charinthipen_US
dc.contributor.authorChanthasenanont, Athitaen_US
dc.date.accessioned2009-05-27T20:24:20Z
dc.date.available2009-05-27T20:24:20Z
dc.date.issued2007-09-26en_US
dc.descriptionChotmaihet Thangphaet.en_US
dc.description.abstractOBJECTIVE: To study the efficacy of ginger and dimenhydrinate in the treatment of nausea and vomiting in pregnancy. STUDY DESIGN: Double blind randomized controlled trial. SETTING: Department of Obstetrics and Gynecology, Thammasat Hospital, Faculty of Medicine, Thammasat University. MATERIAL AND METHOD: Between January 2005 and December 2005, 170 pregnant women who attended at antenatal clinic Thammasat University Hospital with the symptoms of nausea and vomiting in pregnancy were randomly allocated into group A (n = 85) and group B (n = 85). The patients in group A received one capsule of ginger twice daily (one capsule contained 0.5 gm of ginger powder) while the patients in group B received the identical capsule of 50 mg dimenhydrinate twice daily. The visual analogue nausea scores (VANS) and vomiting times were evaluated at day 0-7 of the treatment. RESULTS: There was no significant difference in the visual analogue nausea scores (VANS) between group A and group B in day 1-7 of the treatment. The vomiting episodes of group A were greater than group B during the first and second day of the treatment with statistically significant difference. No difference in vomiting episodes during the day 3-7 of treatment was found in both groups. There was a statistically significant difference in the side effect of drowsiness after treatment in group B greater (77.64%) than group A (5.88%) (p < 0.01). CONCLUSION: From the presented data, ginger is as effective as dimenhydrinate in the treatment of nausea and vomiting during pregnancy and has fewer side effects.en_US
dc.description.affiliationDepartment of Obstetrics and Gynecology, Faculty of Medicine, Thammasat University, Pathumthani 12120, Thailand. pongrojpaw@hotmail.comen_US
dc.identifier.citationPongrojpaw D, Somprasit C, Chanthasenanont A. A randomized comparison of ginger and dimenhydrinate in the treatment of nausea and vomiting in pregnancy. Journal of the Medical Association of Thailand. 2007 Sep; 90(9): 1703-9en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/42936
dc.language.isoengen_US
dc.source.urihttps://www.mat.or.th/journal/all.phpen_US
dc.subject.meshAdulten_US
dc.subject.meshAntiemetics --pharmacologyen_US
dc.subject.meshDimenhydrinate --pharmacologyen_US
dc.subject.meshFemaleen_US
dc.subject.meshGingeren_US
dc.subject.meshHumansen_US
dc.subject.meshNausea --drug therapyen_US
dc.subject.meshPregnancyen_US
dc.subject.meshPregnancy Complications --drug therapyen_US
dc.subject.meshSickness Impact Profileen_US
dc.subject.meshTreatment Outcomeen_US
dc.subject.meshVomiting --drug therapyen_US
dc.titleA randomized comparison of ginger and dimenhydrinate in the treatment of nausea and vomiting in pregnancy.en_US
dc.typeClinical Trialen_US
dc.typeJournal Articleen_US
dc.typeRandomized Controlled Trialen_US
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