Clinical profile of acute kidney injury in patients admitted to medical wards in a tertiary care setting

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dc.contributor.authorSoren, Ben_US
dc.contributor.authorPapareddy, Aen_US
dc.contributor.authorKommareddy, SRen_US
dc.contributor.authorMeriga, RKen_US
dc.contributor.authorMidathala, NVen_US
dc.contributor.authorSarikonda, GRen_US
dc.date.accessioned2020-09-24T07:55:59Z
dc.date.available2020-09-24T07:55:59Z
dc.date.issued2019-02
dc.description.abstractBackground: Acute kidney injury (AKI) is a global problem. Its incidence varies in different geographical region as well as the targeted population under the study. Most common causes are sepsis, volume depletion, nephrotoxic medication, and illnesses related to the heart and liver. In developing countries, it can be due to snake bite, malaria, and secondary to poisonings. Objectives: The study is conducted to analyze the types, etiological factors, and comorbidities associated with AKI in patients admitted into the medical wards in a tertiary care hospital. Materials and Methods: A total of 60 patients were selected based on the Kidney Disease Improving Global Outcomes criteria of AKI. An increase in serum creatinine >0.3 mg/dl or >1.5 times the baseline and a fall of urine output <0.5 ml/kg/h for 6–12 h were the criteria for selection. A history of volume depletion, nephrotoxic drugs, febrile illness, trauma, surgeries, diabetes mellitus, hypertension, and any history of cardiovascular, renal, and liver disorders was taken. Patients were classified into pre-renal, renal, and post-renal as per etiologies found during the study. Data collected were analyzed statistically. Results: Of 60 patients, 39 were males and 21 were females. The mean age of the study group was 60 ± 5. Diabetes and hypertension were the most common comorbidities. Infections were found to be most common cause which included diarrheal illness (12 patients) followed by urinary tract infection (10 patients) and community-acquired pneumonia (8 patients). Nonsteroidal anti-inflammatory drug abuse was seen in 12 patients, and an equal number of patients had chronic kidney disease and 6 patients had coronary artery disease. Conclusion: Pre-renal AKI is one of the common complications in the hospitalized patients. The key to management lies in high index of suspicion and early intervention while the injury is still reversible.en_US
dc.identifier.affiliationsDepartment of General Medicine, Narayana Medical College and Hospital, Nellore, Andhra Pradesh, Indiaen_US
dc.identifier.citationSoren B, Papareddy A, Kommareddy SR, Meriga RK, Midathala NV, Sarikonda GR. Clinical profile of acute kidney injury in patients admitted to medical wards in a tertiary care setting. International Journal of Medical Science and Public Health. 2019 Feb; 8(2): 110-113en_US
dc.identifier.issn2277-338X
dc.identifier.issn2320-4664
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/205389
dc.languageenen_US
dc.publisherInternational Journal of Medical Science and Public Healthen_US
dc.relation.issuenumber2en_US
dc.relation.volume8en_US
dc.source.urihttps://dx.doi.org/10.5455/ijmsph.2019.0927727102018en_US
dc.subjectAcute Kidney Injuryen_US
dc.subjectKidney Disease Improving Global Outcomes Guidelinesen_US
dc.subjectInfectionsen_US
dc.titleClinical profile of acute kidney injury in patients admitted to medical wards in a tertiary care settingen_US
dc.typeJournal Articleen_US
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