Sarcoidosis presenting as ovarian mass with omental and peritoneal nodules with elevated CA 125 level; mimicking malignancy

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dc.contributor.authorBadanale, Renukaen_US
dc.date.accessioned2024-09-24T10:58:45Z
dc.date.available2024-09-24T10:58:45Z
dc.date.issued2023-11
dc.description.abstractSarcoidosis is a systemic inflammatory disease of unknown aetiology with a variety of nonspecific clinicoradiological features making diagnosis challenging. Sarcoidosis commonly involves pulmonary and lymphoreticular systems; ovarian involvement being extremely rare. We present a case of a 50-year Indian postmenopausal female, with a history of abdominal pain and distension, referred from the peripheral hospital for management of a solid complex left adnexal mass and elevated CA 125 levels. Based on ultrasonography and contrast-enhanced computed tomography, ovarian carcinoma was a differential diagnosis. Ascitic and pleural fluid cytology and ovarian fine needle aspiration cytology (FNAC) didnꊰ give any conclusive diagnosis. Hence surgical intervention was carried out. Histopathology revealed noncaseating granulomas in ovaries, peritoneum, and omentum. Tissue polymerase chain reaction (PCR) for tuberculous and nontuberculous mycobacteria was negative. Post-operatively serum angiotensin-converting enzyme (ACE) and calcium levels were elevated. These findings supported the diagnosis of sarcoidosis and the patient responded well to systemic steroids.en_US
dc.identifier.affiliationsDepartment Pathology, Rashtrasant Tukdoji Tertiary Care Cancer Centre, Nagpur, Maharashtra, Indiaen_US
dc.identifier.citationBadanale Renuka . Sarcoidosis presenting as ovarian mass with omental and peritoneal nodules with elevated CA 125 level; mimicking malignancy . International Journal of Reproduction, Contraception, Obstetrics and Gynecology . 2023 Nov; 12(11): 3414-3416en_US
dc.identifier.issn2320-1770
dc.identifier.issn2320-1789
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/234706
dc.languageenen_US
dc.publisherMedip Academyen_US
dc.relation.issuenumber11en_US
dc.relation.volume12en_US
dc.source.urihttps://doi.org/10.18203/2320-1770.ijrcog20233322en_US
dc.subjectCA 125en_US
dc.subjectOmental nodulesen_US
dc.subjectOvarian massen_US
dc.subjectSarcoidosisen_US
dc.titleSarcoidosis presenting as ovarian mass with omental and peritoneal nodules with elevated CA 125 level; mimicking malignancyen_US
dc.typeJournal Articleen_US
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