The seroprevalence of human herpesvirus 8 infection in the Thai population.

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dc.contributor.authorAyuthaya, Panasda Isarangkura Naen_US
dc.contributor.authorKatano, Harutakaen_US
dc.contributor.authorInagi, Reikoen_US
dc.contributor.authorAuwanit, Wattanaen_US
dc.contributor.authorSata, Tetsutaroen_US
dc.contributor.authorKurata, Takeshien_US
dc.contributor.authorYamanishi, Koichien_US
dc.date.accessioned2009-05-27T15:22:19Z
dc.date.available2009-05-27T15:22:19Z
dc.date.issued2002-06-19en_US
dc.descriptionThe Southeast Asian Journal of Tropical Medicine and Public Health.en_US
dc.description.abstractThe seroprevalence of human herpesvirus 8 (HHV-8) infection in the Thai population was investigated. Sera from 1,018 human immunodeficiency virus 1 (HIV-1)-negative and 436 HIV-1-positive individuals were tested for antibodies to latent and lytic HHV-8 antigens by indirect immunofluorescence assay (IFA) and an enzyme-linked immunosorbent assay (ELISA) using mixed recombinant orf HHV-8 proteins. The positive sera were further tested with recombinant HHV-8 protein expressed 293T cells by IFA. The seroprevalence of HHV-8 infection was determined by the concordant reactivity of sera among antibody testing assays. The results showed a low rate of HHV-8 seropositivity in both HIV-1-negative healthy individuals (0.6%) and HIV-1-infected patients (0.7%). These results are consistent with the fact that a small number of patients with AIDS-associated KS have been reported in Thailand and that HHV-8 is an uncommon pathogen in this country. Interestingly, we found that sera from the general population living in the north, but not other regions of Thailand, had antibodies to HHV-8.en_US
dc.description.affiliationDepartment of Microbiology, Osaka University Medical School, Japan.en_US
dc.identifier.citationAyuthaya PI, Katano H, Inagi R, Auwanit W, Sata T, Kurata T, Yamanishi K. The seroprevalence of human herpesvirus 8 infection in the Thai population. The Southeast Asian Journal of Tropical Medicine and Public Health. 2002 Jun; 33(2): 297-305en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/32618
dc.language.isoengen_US
dc.source.urihttps://www.tm.mahidol.ac.th/seameo/2002_33_2/16-2850.pdfen_US
dc.subject.meshAntibodies, Viral --blooden_US
dc.subject.meshChilden_US
dc.subject.meshEnzyme-Linked Immunosorbent Assayen_US
dc.subject.meshHerpesviridae Infections --epidemiologyen_US
dc.subject.meshHerpesvirus 8, Human --immunologyen_US
dc.subject.meshHumansen_US
dc.subject.meshSensitivity and Specificityen_US
dc.subject.meshSeroepidemiologic Studiesen_US
dc.subject.meshThailand --epidemiologyen_US
dc.titleThe seroprevalence of human herpesvirus 8 infection in the Thai population.en_US
dc.typeJournal Articleen_US
dc.typeResearch Support, Non-U.S. Gov'ten_US
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