Gastrointestinal stromal tumors the assessment of malignant potential.

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dc.contributor.authorNada, Ren_US
dc.contributor.authorVaiphei, Ken_US
dc.contributor.authorSingh, Ren_US
dc.contributor.authorWig, J Den_US
dc.contributor.authorGupta, N Men_US
dc.contributor.authorBanerjee, A Ken_US
dc.date.accessioned2001-10-31en_US
dc.date.accessioned2009-05-29T11:45:59Z
dc.date.available2001-10-31en_US
dc.date.available2009-05-29T11:45:59Z
dc.date.issued2001-10-31en_US
dc.description.abstractGISTS are the largest category of non-epithelial neoplasms of stomach and small bowel. Numerous immunohistochemical, ultrastructural and flow cytometry studies have been carried out for evaluation of prognostic factors which could predict malignant behaviour of these neoplasms. Tumor size of 5 cm and mitosis of 2/10 hpf were suggested as two important parameters which could predict the chances of recurrence and clinically aggressive course. The aim of this study is to examine predictive value of these two important parameters in assigning the tumors as high, intermediate and low risk groups. Using these two parameters we categorized 30 cases of GIST over a period of 6 years (1990-95) into low, intermediate and high risk groups and examined other features of these cases. Based on these two parameters alone we found that 4 cases each in low and intermediate group could be assigned to a higher risk group clinically as there were presence of adjacent organ infiltration, lymphatic emboli, serosal nodules, lymph node metastasis and transmural infiltration. Hence, other features like hemorrhage, necrosis and anaplasia should also be included in risk assessment. Metaplastic tissues like bone, cartilage and adipose tissues were seen only in high-risk categories.en_US
dc.description.affiliationDepartment of Histopathology, Postgraduate Institute of Medical Education & Research, Chandigarh.en_US
dc.identifier.citationNada R, Vaiphei K, Singh R, Wig JD, Gupta NM, Banerjee AK. Gastrointestinal stromal tumors the assessment of malignant potential. Indian Journal of Pathology & Microbiology. 2001 Oct; 44(4): 393-7en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/73871
dc.language.isoengen_US
dc.source.urihttps://www.ijpmonline.orgen_US
dc.subject.meshAdolescenten_US
dc.subject.meshAdulten_US
dc.subject.meshAgeden_US
dc.subject.meshAged, 80 and overen_US
dc.subject.meshFemaleen_US
dc.subject.meshGastrointestinal Neoplasms --pathologyen_US
dc.subject.meshHumansen_US
dc.subject.meshIntestine, Small --pathologyen_US
dc.subject.meshMaleen_US
dc.subject.meshMiddle Ageden_US
dc.subject.meshMitotic Indexen_US
dc.subject.meshNeoplasms, Connective Tissue --pathologyen_US
dc.subject.meshPredictive Value of Testsen_US
dc.subject.meshPrognosisen_US
dc.subject.meshRetrospective Studiesen_US
dc.subject.meshStomach --pathologyen_US
dc.subject.meshStromal Cells --pathologyen_US
dc.titleGastrointestinal stromal tumors the assessment of malignant potential.en_US
dc.typeJournal Articleen_US
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