Cord Blood Nucleated RBC as a Predictor of Perinatal Asphyxia, Severity and Outcome.
Loading...
Date
2014-03
Journal Title
Journal ISSN
Volume Title
Publisher
Abstract
Objective: To study the correlation of cord blood nucleated red blood cell (NRBC)/100 white blood cell (WBC) count with
perinatal asphyxia in terms of severity and short-term outcome. Material and methods: A prospective, comparative case-control
study was undertaken in a tertiary care hospital from January 2011 to December 2012, which included a total of 200 neonates
with 100 asphyxiated babies (case group) and 100 normal babies (control group). The cord blood was collected immediately
after delivery for measurement of NRBC/100 WBC, and pH. Early neonatal outcome of both groups was also evaluated in
relation to the NRBC/100 WBC count. Statistical analysis was performed with chi-square and student t-test. Results: The mean
NRBC/100 WBC count was 50.82 ± 23.85 (range from 5 to 106) in case group and 1.67 ± 1.005 (range from 0 to 13) in control
group (p < 0.001). Also a statistically significant correlation existed between severity of asphyxia (stage of hypoxic-ischemic
encephalopathy [HIE]), poor outcome and higher number of NRBC/100 WBC count (p < 0.001). Conclusion: It is an inexpensive
and easily available procedure to evaluate perinatal asphyxia, specially in a resource poor country like ours, where blood gas
analysis facilities are not available in majority of places. Also, it is a good predictor of short-term outcome of asphyxiated babies.
Description
Keywords
Cord blood, nucleated red blood cells, perinatal, asphyxia
Citation
Mohanty Anil Kumar, Das Leena, Pradhan Subal, Meher Bijay, Beriha Siba Shankar. Cord Blood Nucleated RBC as a Predictor of Perinatal Asphyxia, Severity and Outcome. Indian Journal of Clinical Practice. 2014 Mar; 24(10): 983-986.