Mechanism of store-operated calcium entry.

Simple item page
dc.contributor.authorDutta, Den_US
dc.date.accessioned2000-12-20en_US
dc.date.accessioned2009-06-01T15:05:38Z
dc.date.available2000-12-20en_US
dc.date.available2009-06-01T15:05:38Z
dc.date.issued2000-12-20en_US
dc.description34 references.en_US
dc.description.abstractActivation of receptors coupled to the phospholipase C/IP3 signalling pathway results in a rapid release of calcium from its intracellular stores, eventually leading to depletion of these stores. Calcium store depletion triggers an influx of extracellular calcium across the plasma membrane, a mechanism known as the store-operated calcium entry or capacitative calcium entry. Capacitative calcium current plays a key role in replenishing calcium stores and activating various physiological processes. Despite considerable efforts, very little is known about the molecular nature of the capacitative channel and the signalling pathway that activates it. This review summarizes our current knowledge about store operated calcium entry and suggests possible hypotheses for its mode of activation.en_US
dc.description.affiliationNational Centre for Biological Sciences, UAS Campus, GKVK, Bangalore 560 065, India. devkanya@ncbs.res.inen_US
dc.identifier.citationDutta D. Mechanism of store-operated calcium entry. Journal of Biosciences. 2000 Dec; 25(4): 397-404en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/111297
dc.language.isoengen_US
dc.source.urihttps://www.ias.ac.in/jbiosci/index.htmlen_US
dc.subject.mesh1-Phosphatidylinositol 3-Kinase --metabolismen_US
dc.subject.meshAnimalsen_US
dc.subject.meshCalcium --metabolismen_US
dc.subject.meshCalcium Channels --metabolismen_US
dc.subject.meshCell Membrane --metabolismen_US
dc.subject.meshCytosol --metabolismen_US
dc.subject.meshHumansen_US
dc.subject.meshModels, Biologicalen_US
dc.subject.meshSignal Transductionen_US
dc.titleMechanism of store-operated calcium entry.en_US
dc.typeJournal Articleen_US
dc.typeReviewen_US
Files
License bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
license.txt
Size:
1.79 KB
Format:
Plain Text
Description:
Download
Collections
Journal of Biosciences