Loss of lateral femoral condyle following sepsis of knee region in infancy: The hypothesis of vascular pathogenesis and clinical course

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dc.contributor.authorAgarwal, Aen_US
dc.contributor.authorJethwa, Ren_US
dc.date.accessioned2024-12-07T11:14:11Z
dc.date.available2024-12-07T11:14:11Z
dc.date.issued2024-07
dc.description.abstractComplete loss of lateral femoral condyle of the femur following sepsis of the knee region in infancy is a well-recognized entity. The etiopathogenesis of the sequelae is poorly understood with synovial plicae and post-septic growth disturbance postulated as possible causes. Two illustrative cases are presented to elucidate the clinical effects of condylar loss in the pediatric age group.There is a typical pattern of unicondylar damage, loss of adjacent metaphysis, and metaphyseal spur in involved cases. Abnormal loading of the knee, ligament laxity, and the presence of a physeal bar contribute additionally to deformity. The deformity progression can be as rapid as 2.8 degrees per month. The lesion is most often treated by balancing the knee mechanics using osteotomies and growth modulations. The lesion progresses downhill due to the absence of lateral support of the knee joint configuration. The anatomical region supplied by the superior lateral genicular vessels closely matches with the lateral unicondylar femoral loss seen post-sepsis. A vascular etiology is therefore hypothesized for the lesion.en_US
dc.identifier.affiliationsDepartment of Pediatric Orthopedics, Chacha Nehru Bal Chikitsalaya, Delhi, Indiaen_US
dc.identifier.affiliationsDepartment of Pediatric Orthopedics, Chacha Nehru Bal Chikitsalaya, Delhi, Indiaen_US
dc.identifier.citationAgarwal A, Jethwa R. Loss of lateral femoral condyle following sepsis of knee region in infancy: The hypothesis of vascular pathogenesis and clinical course . Annals of the National Academy of Medical Sciences (India). 2024 Jul; 60(3): 231-235en_US
dc.identifier.issn0379-038X
dc.identifier.issn2454-5635
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/241071
dc.languageenen_US
dc.publisherNational Academy of Medical Sciencesen_US
dc.relation.issuenumber3en_US
dc.relation.volume60en_US
dc.source.urihttps://dx.doi.org/10.25259/ANAMS-2022-8-10-(714)en_US
dc.subjectInfectionen_US
dc.subjectLateral femoral condyleen_US
dc.subjectLossen_US
dc.subjectSepsisen_US
dc.titleLoss of lateral femoral condyle following sepsis of knee region in infancy: The hypothesis of vascular pathogenesis and clinical courseen_US
dc.typeJournal Articleen_US
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