Correlations between Quality of Vision, Higher Order Aberrations and Non-Invasive Keratographic Tear Film Break-Up Time in Pseudophakic Eyes after Uncomplicated Phacoemulsification

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dc.contributor.authorHutauruk, Jen_US
dc.contributor.authorGondhowiardjo, T. Den_US
dc.contributor.authorSuhardjoen_US
dc.contributor.authorSasongko, M. B.en_US
dc.date.accessioned2023-07-14T07:02:00Z
dc.date.available2023-07-14T07:02:00Z
dc.date.issued2022-07
dc.description.abstractAims: In this study, we aimed to investigate the intercorrelations between tear film break up time, measured non-invasively using non-invasive keratographic break-up time (NIKBUT), higher order aberrations (HOA) and quality of vision (QoV) in pseudophakic patients.Study Design: Cross-sectional.Methods: Thirty-five pseudophakic aged patients aged 50 years or older, and 35 control phakic patients aged 17 to 23 years with corrected visual acuity of 20/20 were included in this study. All subjects underwent similar examination including QoV questionnaire, aberrometry to measure HOA, and NIKBUT. HOA was measured with the OPD-Scan/ ARK 10000 corneal analyzer (Nidek CO. Ltd), expressed as Root Mean Square (RMS) HOA and NIKBUT was assessed using non-invasive TF-Scan module Keratograph 5M (K5M), equipped with modified tear film scanning function (Oculus, Wetzlar, Germany). Statistical analysis was performed to find the correlation between NIKBUT, HOA and QoV.Results: Patients in the pseudophakic group were significantly older (median age 66 vs. 20 years; P<0.01), had shorter NIKBUT (10.5 vs. 17.2; P<0.01), lower QoV score (1.63 vs. 0.68; P=0.04), and higher RMS HOA (0.5 vs. 0.26; P<0.01) compared to control group. NIKBUT was inversely correlated with RMS HOA (r = -0.19; p = 0.03) and RMS HOA was significantly correlated with QoV, even after adjustment for age and gender (r = -0.21; P0.04). NIKBUT <9.93s was correlated with lower QoV. The area under the curve was 0.81 (95% CI = 0.67 � 0.95, p = 0.012), and had 100% sensitivity and 61% specificity.Conclusion: Shorter NIKBUT was correlated with greater HOA and greater HOA was correlated with lower QoV. NIKBUT value of shorter than 9.93s could potentially predict pseudophakic patients who will likely experience visual symptoms leading to decreased QoV; thus, the use of artificial tears might be beneficial.en_US
dc.identifier.affiliationsJEC Hospitals and Clinics,Jakarta, Indonesiaen_US
dc.identifier.affiliationsDepartment of Ophthalmology, Faculty of Medicine, Public Health and Nursing, Universitas Gadjah Mada -Sardjito Eye Center, Dr. Sardjito General Hospital, Yogyakarta, Indonesia.en_US
dc.identifier.citationHutauruk J, Gondhowiardjo T. D, Suhardjo, Sasongko M. B.. Correlations between Quality of Vision, Higher Order Aberrations and Non-Invasive Keratographic Tear Film Break-Up Time in Pseudophakic Eyes after Uncomplicated Phacoemulsification. Ophthalmology Research: An International Journal. 2022 Jul; 16(4): 7-15en_US
dc.identifier.issn2321�27
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/218409
dc.languageenen_US
dc.publisherSciencedomain Internationalen_US
dc.relation.issuenumber4en_US
dc.relation.volume16en_US
dc.source.urihttps://doi.org/10.9734/or/2022/v16i430240en_US
dc.subjectHigher order aberrationsen_US
dc.subjectnon-invasive keratographic break-up timeen_US
dc.subjectphacoemulsificationen_US
dc.subjectpseudophakicen_US
dc.subjectquality of visionen_US
dc.subjecttear filmen_US
dc.titleCorrelations between Quality of Vision, Higher Order Aberrations and Non-Invasive Keratographic Tear Film Break-Up Time in Pseudophakic Eyes after Uncomplicated Phacoemulsificationen_US
dc.typeJournal Articleen_US
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