Chemical compositions and hypoglycemic activities of the protein and mucilage of Casimiroa edulis (Llave & Lex) seeds and fruits

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japs2019v9n10p084.pdf (1.97 MB)
Date
2019-10
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Open Science Publishers LLP
Abstract
During the present study, chemical compositions of the protein and mucilage of seeds and fruits of Casimiroa edulis(Llave & Lex) as well as their hypoglycemic effects and other related biochemical parameters were studied for thefirst time. The protein content of C. edulis seeds was prepared with 4% (w/w) yield. The amino acid analyzer ofprotein hydrolysates led to the identification of 17 amino acids. Glutamic acid (10.25%) was considered the majoramino acid. Moreover, the mucilage content of C. edulis fruits was prepared with 11% (w/w) yield. GLC analysis ofmucilage hydrolysates revealed the identification of ten sugars represented (87.19%), with galacturonic acid (31.23%)as the main component. Significant hypoglycemic effects of protein and mucilage were recorded with respect tocontrol and glibenclamide (standard drug). In addition, histopathological examination was performed, and theresults showed that treatment with protein and mucilage remarkably improved Alanine Aminotransferase, AspartateAminotransferase, and Alkaline Phosphatase activities after streptozotocin induction with respect to control, alsoameliorated the disturbances in Gamma Glutamyl Transferase, total protein & albumin, Glutathione levels, Catalaseand lipid peroxidation activities. The prepared protein and mucilage exhibited properties that recommend them asnatural supplements or in food industries for improving human being health.
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Keywords
ALP, Casimiroa edulis, histopathological, mucilage, protein, streptozotocin
Citation
Ibrahim Nabawyea, Seham El Hawary, Magdy Mohammed, Sanaa Ali, Zeinab Kandil, Esraa Refaat. Chemical compositions and hypoglycemic activities of the protein and mucilage of Casimiroa edulis (Llave & Lex) seeds and fruits. Journal of Applied Pharmaceutical Science. 2019 Oct; 2019 Oct: 084-091
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https://imsear.searo.who.int/handle/123456789/210467
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Journal of Applied Pharmaceutical Science (JAPS)