A Study of Prevalence of Aerobic Bacteria and Fungi in Sputum Specimens of Patients with Post Tubercular Bronchiectasis

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dc.contributor.authorKumar, G Sen_US
dc.contributor.authorLal, S Ben_US
dc.contributor.authorLaxmikanth, Men_US
dc.date.accessioned2019-11-04T04:57:57Z
dc.date.available2019-11-04T04:57:57Z
dc.date.issued2017-02
dc.description.abstractBackground: Patients with Post TB bronchiectasis colonize many aerobic bacteria and fungi and lead to an increase in exacerbations and decrease in quality of life. Objective: To study the prevalence of aerobic bacteria and fungi in sputum specimens of patients with post tubercular bronchiectasis and to find out the local antibiotic sensitivity and resistance patterns. Materials and Methods: This prospective observational study was carried out over a period of one year comprising of 50 patients with post Tubercular Bronchiectasis who were above 18 yrs, completed ATT smear negative and HRCT showing bronchiectactic changes. Identification of organisms from sputum samples were done by classical aerobic microbial staining and culture methods. Descriptive and inferential statistical analysis was carried out in this study. Results: This study comprises of the 50 patients with a larger group of individuals under the age group of 51-60 (30%), along with bronchial colonization of aerobic bacteria being 78% and growth of fungi being 2%.Among the 39 patients,16 patients (32%) had grown Pseudomonas aeruginosa, 12 patients(24%) had grown Klebsiella pneumoniae, 8 patients(16%) had grown Streptococcus species and rest 3 patients(6%) had grown staphylococcus species. The Antibiotic resistance noted highest being Amikacin (56.4%), piperacillin-tazobactam showing the least (2.6%) and highest sensitivity with imipenem(100%). Conclusion: This study signifies that prevalence of aerobic bacteria, especially Pseudomonas aeruginosa and Klebsiella pneumonia was common in patients with post tubercular bronchiectasis. The Antibiotic resistance noted highest being Amikacin (56.4%) and sensitivity with imipenem(100%). In patients colonizing Pseudomonas aeruginosa, there was significant decline in lung function.en_US
dc.identifier.affiliationsAssistant Professor, Department of Pulmonary Medicine SMC, Vijayawada Affiliated to Dr NTR University of Health sciences Vijayawada, Indiaen_US
dc.identifier.affiliationsProfessor & HOD, Department of Pulmonary Medicine SMC, Vijayawada Affiliated to Dr NTR University of Health sciences Vijayawada, India, drsblal@yahoo.co.inen_US
dc.identifier.affiliationsMD, Junior Resident, Department of Pulmonary Medicine SMC, Vijayawada Affiliated to Dr NTR University of Health sciences Vijayawada, India, mudragadalaxmikanth@gmail.comen_US
dc.identifier.citationKumar G S, Lal S B, Laxmikanth M. A Study of Prevalence of Aerobic Bacteria and Fungi in Sputum Specimens of Patients with Post Tubercular Bronchiectasis. International Journal of Medical and Dental Sciences. 2017 Jul; 6(2): 1468-1474en_US
dc.identifier.issn2454-8952
dc.identifier.issn2320-1118
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/183613
dc.languageenen_US
dc.publisherDr. J.S. Sodhi Memorial Educational Societyen_US
dc.relation.issuenumber2en_US
dc.relation.volume6en_US
dc.source.urihttps://doi.org/10.18311/ijmds/2017/18834en_US
dc.subjectBronchiectasisen_US
dc.subjectPulmonary Tuberculosisen_US
dc.subjectAntibiotic Sensitivityen_US
dc.subjectAntibiotic Resistanceen_US
dc.subjectPulmonologyen_US
dc.titleA Study of Prevalence of Aerobic Bacteria and Fungi in Sputum Specimens of Patients with Post Tubercular Bronchiectasisen_US
dc.typeJournal Articleen_US
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