Airway Pressure Release Ventilation: An Alternative Ventilation Mode for Pediatric Acute Hypoxemic Respiratory Failure.
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Date
2010-11
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Volume Title
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Abstract
Airway pressure release ventilation (APRV) is a
relatively new mode of mechanical ventilation. The use of
this model of ventilation in pediatrics has been limited. The
authors describe their experience with this mode of
ventilation in a series of pediatric hypoxemic respiratory
failure patients. Three patients with acute hypoxemic
respiratory failure (AHRF) were treated with APRV, when
oxygenation did not improve with pressure control ventilation
(PCV). The mean age of the patients was 5.8±
1.3 months. Fractional oxygen concentration decreased
from 0.97±0.02 for PCV to 0.68±0.12 for APRV, peak
airway pressure fell from 36.6±11.5 cm H2O for PCV to
33.3±5.7 cm H2O for APRV, mean airway pressure
increased from 17.9±5.9 cmH2O for PCV to 27±
2.6 cmH2O for APRV and release tidal volume increased
from 8.3±1.5 mL/kg for PCV to 13.2±1.1 mL/kg for
APRV after 1 h. APRV may improve oxygenation in
pediatric AHRF when conventional mechanical ventilation
fails. The APRV modality may provide better oxygenation
with lower peak airway pressure.
Description
Keywords
Airway pressure release ventilation, Acute hypoxemic respiratory failure, Oxygenation, Pediatrics, Hypoxemia
Citation
Demirkol Demet, Karabocuoglu Metin, Citak Agop. Airway Pressure Release Ventilation: An Alternative Ventilation Mode for Pediatric Acute Hypoxemic Respiratory Failure. Indian Journal of Pediatrics. 2010 Nov ; 77 (11): 1322-1325.