The problem of emerging chloramphenicol resistance in typhoid fever--a preliminary report.

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dc.contributor.authorAgarwal, Sen_US
dc.contributor.authorMadhu, S Ven_US
dc.contributor.authorGuleria, J Sen_US
dc.contributor.authorTalwar, Ven_US
dc.date.accessioned1991-06-01en_US
dc.date.accessioned2009-05-30T22:55:39Z
dc.date.available1991-06-01en_US
dc.date.available2009-05-30T22:55:39Z
dc.date.issued1991-06-01en_US
dc.description.abstractDrug sensitivity of Salmonella typhi isolated from 25 blood culture positive cases of typhoid fever who presented between May and July 1990 was tested to determine their in vitro susceptibility to various antimicrobials. Twenty-one of them (84%) showed resistance to chloramphenicol and 24 (96%) to cotrimoxazole. All the 25 cases were sensitive to norfloxacin, gentamicin and cephalexin. Sixteen of 21 chloramphenicol resistant typhoid cases in whom chloramphenicol was initially started failed to respond to this drug even after 5 to 7 days, thereby indicating that in vivo response matched with the in vitro sensitivity. Clinical response to norfloxacin, whether given initially or following chloramphenicol failure, was prompt and satisfactory. Norfloxacin thus appears to be a good choice in such cases.en_US
dc.description.affiliationDepartment of Medicine, UCMS and GTB Hospital, Shahdara, Delhi.en_US
dc.identifier.citationAgarwal S, Madhu SV, Guleria JS, Talwar V. The problem of emerging chloramphenicol resistance in typhoid fever--a preliminary report. Journal of the Association of Physicians of India. 1991 Jun; 39(6): 443-4en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/89966
dc.language.isoengen_US
dc.source.urihttps://www.japi.orgen_US
dc.subject.meshChloramphenicol --therapeutic useen_US
dc.subject.meshChloramphenicol Resistanceen_US
dc.subject.meshDisease Outbreaksen_US
dc.subject.meshHumansen_US
dc.subject.meshIndia --epidemiologyen_US
dc.subject.meshMicrobial Sensitivity Testsen_US
dc.subject.meshNorfloxacin --therapeutic useen_US
dc.subject.meshSalmonella typhi --drug effectsen_US
dc.subject.meshTyphoid Fever --drug therapyen_US
dc.titleThe problem of emerging chloramphenicol resistance in typhoid fever--a preliminary report.en_US
dc.typeJournal Articleen_US
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