Comparing outcomes in new pulmonary sputum positive and sputum negative cases under RNTCP in rural India.
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Date
2009-07
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Abstract
Setting: The study was carried out at the Bagula TU, Nadia, West Bengal, India.
Objective: To find out the treatment outcomes of new smear negative cases, in low HIV prevalence population, and to
compare the results with new smear positive cases in the same population.
Design: It was a retrospective record based study. All patients registered between January 1999 and June 2005 were divided
into new smear positive and new smear negative groups and the difference in the outcomes analysed.
Results: Favourable outcome was less in new smear negative cases, compared to new smear positive (84% vs. 86%, p=
0.002).Death and default were more in new smear negative cases, compared to new smear positive (death: 6.8% vs. 3.7%;
default: 6.02% vs. 4.18%), (p < 0.05). Failure and transferred out were non- significantly higher in new smear positive
group.
Conclusions: Smear negative patients had a worse treatment outcome compared to smear positive patients including lower
favourable outcomes and higher deaths and defaults. The possible reasons need to be explored and corrective actions need
to be taken accordingly.
Description
Keywords
Tuberculosis, Treatment outcome, RNTCP
Citation
Mukherjee Abhijit, Singla Rupak, Saha Indrani. Comparing outcomes in new pulmonary sputum positive and sputum negative cases under RNTCP in rural India. Indian Journal of Tuberculosis. 2009 Jul; 56(3): 144-150.