Male breast cancer in Indian patients: Is it the same.

dc.contributor.authorChikaraddi, S B
dc.contributor.authorKrishnappa, R
dc.contributor.authorDeshmane, V
dc.date.accessioned2013-01-22T07:16:34Z
dc.date.available2013-01-22T07:16:34Z
dc.date.issued2012-07
dc.description.abstractBackground: Cancer of the male breast accounts for about 1% of all malignancies in men and 1% of all breast cancers. Poor level of awareness often results in late presentation and delayed diagnosis in our environment. This study was done to analyse the demographic data, management and survival of male breast cancers in Indian subset of patients and compare it with that of western literature. Materials and Methods: A 10 year (2001-2010) retrospective study of all male breast cancers was done. Data regarding the incidence, presentation, histopathology, stage and grade of tumor, management and outcome of patients were analysed. Results: 26 cases of male breast cancer were encountered. This comprised 0.4% of all breast cancers seen in our department during the 10 year period. The ages of patients ranged from 45-75 years with a mean age of 57 years. Family history was present in 4 patients. Clinically, symptoms included self-detected lump in 23 (88.5%) patients, nipple retraction in 12 (46.1%) and pain in 12 (46.1%). All cases were unilateral (16 on right, 10 on left). Disease most commonly involved central quadrant (9 patients). Grade 3 disease was found in 13 patients and Stage 3 disease was most commonly encountered (13 patients). None of our patients received neo adjuvant chemotherapy. 20 (76.9%) patients had modified radical mastectomy and 6 (23.1%) had radical mastectomy. Most of our patients were hormone receptor positive (21 patients). Bilateral orchidectomy, Adjuvant chemotherapy, Adjuvant radiotherapy and Tamoxifen were offered in 3 (11.5%), 16 (61.5%), 17 (65.4%) and 15 (57.7%) patients respectively. Follow up ranged from 1-59 months. Conclusion: Male breast cancer is rare in our centre. Late presentation with advanced disease is a common feature in our environment. Further multiinstitutional, prospective studies are needed for better understanding of management of male breast cancers in Indian subset of patients.en_US
dc.identifier.citationChikaraddi S B, Krishnappa R, Deshmane V. Male breast cancer in Indian patients: Is it the same. Indian Journal of Cancer. 2012 Jul-Sept; 49(3): 272-276.en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/144585
dc.language.isoenen_US
dc.source.urihttps://www.indianjcancer.com/article.asp?issn=0019-509X;year=2012;volume=49;issue=3;spage=272;epage=276;aulast=Chikaraddien_US
dc.subjectMale breast canceren_US
dc.subjectadjuvant therapy in male breast canceren_US
dc.subjectclinicopathology of male breast canceren_US
dc.subject.meshAdult
dc.subject.meshAged
dc.subject.meshBreast Neoplasms, Male --epidemiology
dc.subject.meshBreast Neoplasms, Male --drug therapy
dc.subject.meshBreast Neoplasms, Male --pathology
dc.subject.meshBreast Neoplasms, Male --surgery
dc.subject.meshBreast Neoplasms, Male --therapy
dc.subject.meshChemotherapy, Adjuvant --methods
dc.subject.meshCohort Studies --methods
dc.subject.meshHumans
dc.subject.meshIndia --epidemiology
dc.subject.meshMale
dc.titleMale breast cancer in Indian patients: Is it the same.en_US
dc.typeArticleen_US
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