Normative Values of Cerebral Blood Flow Velocities in Very Low Birth Weight Neonates During First 28 Days of Life

dc.contributor.authorThakur, Anupen_US
dc.contributor.authorJain, Parulen_US
dc.contributor.authorModi, Manojen_US
dc.contributor.authorSingh, Anitaen_US
dc.contributor.authorKansal, Bharaten_US
dc.contributor.authorKler, Neelamen_US
dc.date.accessioned2025-05-09T10:00:42Z
dc.date.available2025-05-09T10:00:42Z
dc.date.issued2024-09
dc.description.abstractObjective: To determine the normative values of cerebral blood flow (CBF) velocities in very low birth weight (VLBW) neonates during the first 28 days of life. Methods: In this prospective observational study, doppler assessment of CBF velocities was performed from the anterior cerebral artery (ACA), middle cerebral artery (MCA) and basilar artery (BA) at 2-8 hours, 24 hours, day 3, 7, 14 and 28 of life. Neonates with gross congenital malformations, those requiring extensive resuscitation at birth, mechanical ventilation with mean airway pressure >12 mbar, requiring inotropes, or those who developed intraventricular hemorrhage (grade II or more) were excluded. Results: A total of 103 VLBW neonates were enrolled, in whom 1178 doppler measurements were recorded. The mean (SD) peak systolic velocity, end diastolic velocity and mean velocity (cm/s) in ACA increased from 26.53 (8.56) to 51.35 (9.36), 9.22 (2.91) to 13.9 (3.24) and 17.75 (3.97) to 25.84 (3.27) respectively from 2 to 8 hours to day 28 of life. In MCA and BA also, CBF velocities increased with post-natal age. Conclusion: We report normative data of CBF velocities in VLBW neonates in first 28 days of life.en_US
dc.identifier.affiliationsDepartment of Neonatology, Institute of Child Health, Sir Ganga Ram Hospital, Rajinder Nagar, New Delhi, Indiaen_US
dc.identifier.affiliationsDepartment of Neonatology, Institute of Child Health, Sir Ganga Ram Hospital, Rajinder Nagar, New Delhi, Indiaen_US
dc.identifier.affiliationsDepartment of Neonatology, Institute of Child Health, Sir Ganga Ram Hospital, Rajinder Nagar, New Delhi, Indiaen_US
dc.identifier.affiliationsDepartment of Neonatology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, Uttar Pradesh, Indiaen_US
dc.identifier.affiliationsDepartment of Neonatology, Institute of Child Health, Sir Ganga Ram Hospital, Rajinder Nagar, New Delhi, Indiaen_US
dc.identifier.affiliationsDepartment of Neonatology, Institute of Child Health, Sir Ganga Ram Hospital, Rajinder Nagar, New Delhi, Indiaen_US
dc.identifier.citationThakur Anup, Jain Parul, Modi Manoj, Singh Anita, Kansal Bharat, Kler Neelam . Normative Values of Cerebral Blood Flow Velocities in Very Low Birth Weight Neonates During First 28 Days of Life. Indian Pediatrics. 2024 Sep; 61(9): 835-838en_US
dc.identifier.issn0974-7559
dc.identifier.issn0019-6061
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/245722
dc.languageenen_US
dc.publisherThe Indian Academy of Pediatricsen_US
dc.relation.issuenumber9en_US
dc.relation.volume61en_US
dc.source.urihttps://indianpediatrics.net/sep2024/835.pdfen_US
dc.subjectEnd diastolic velocityen_US
dc.subjectMean velocityen_US
dc.subjectPeak systolic velocityen_US
dc.titleNormative Values of Cerebral Blood Flow Velocities in Very Low Birth Weight Neonates During First 28 Days of Lifeen_US
dc.typeJournal Articleen_US
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