Normative Values of Cerebral Blood Flow Velocities in Very Low Birth Weight Neonates During First 28 Days of Life
dc.contributor.author | Thakur, Anup | en_US |
dc.contributor.author | Jain, Parul | en_US |
dc.contributor.author | Modi, Manoj | en_US |
dc.contributor.author | Singh, Anita | en_US |
dc.contributor.author | Kansal, Bharat | en_US |
dc.contributor.author | Kler, Neelam | en_US |
dc.date.accessioned | 2025-05-09T10:00:42Z | |
dc.date.available | 2025-05-09T10:00:42Z | |
dc.date.issued | 2024-09 | |
dc.description.abstract | Objective: To determine the normative values of cerebral blood flow (CBF) velocities in very low birth weight (VLBW) neonates during the first 28 days of life. Methods: In this prospective observational study, doppler assessment of CBF velocities was performed from the anterior cerebral artery (ACA), middle cerebral artery (MCA) and basilar artery (BA) at 2-8 hours, 24 hours, day 3, 7, 14 and 28 of life. Neonates with gross congenital malformations, those requiring extensive resuscitation at birth, mechanical ventilation with mean airway pressure >12 mbar, requiring inotropes, or those who developed intraventricular hemorrhage (grade II or more) were excluded. Results: A total of 103 VLBW neonates were enrolled, in whom 1178 doppler measurements were recorded. The mean (SD) peak systolic velocity, end diastolic velocity and mean velocity (cm/s) in ACA increased from 26.53 (8.56) to 51.35 (9.36), 9.22 (2.91) to 13.9 (3.24) and 17.75 (3.97) to 25.84 (3.27) respectively from 2 to 8 hours to day 28 of life. In MCA and BA also, CBF velocities increased with post-natal age. Conclusion: We report normative data of CBF velocities in VLBW neonates in first 28 days of life. | en_US |
dc.identifier.affiliations | Department of Neonatology, Institute of Child Health, Sir Ganga Ram Hospital, Rajinder Nagar, New Delhi, India | en_US |
dc.identifier.affiliations | Department of Neonatology, Institute of Child Health, Sir Ganga Ram Hospital, Rajinder Nagar, New Delhi, India | en_US |
dc.identifier.affiliations | Department of Neonatology, Institute of Child Health, Sir Ganga Ram Hospital, Rajinder Nagar, New Delhi, India | en_US |
dc.identifier.affiliations | Department of Neonatology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, Uttar Pradesh, India | en_US |
dc.identifier.affiliations | Department of Neonatology, Institute of Child Health, Sir Ganga Ram Hospital, Rajinder Nagar, New Delhi, India | en_US |
dc.identifier.affiliations | Department of Neonatology, Institute of Child Health, Sir Ganga Ram Hospital, Rajinder Nagar, New Delhi, India | en_US |
dc.identifier.citation | Thakur Anup, Jain Parul, Modi Manoj, Singh Anita, Kansal Bharat, Kler Neelam . Normative Values of Cerebral Blood Flow Velocities in Very Low Birth Weight Neonates During First 28 Days of Life. Indian Pediatrics. 2024 Sep; 61(9): 835-838 | en_US |
dc.identifier.issn | 0974-7559 | |
dc.identifier.issn | 0019-6061 | |
dc.identifier.place | India | en_US |
dc.identifier.uri | https://imsear.searo.who.int/handle/123456789/245722 | |
dc.language | en | en_US |
dc.publisher | The Indian Academy of Pediatrics | en_US |
dc.relation.issuenumber | 9 | en_US |
dc.relation.volume | 61 | en_US |
dc.source.uri | https://indianpediatrics.net/sep2024/835.pdf | en_US |
dc.subject | End diastolic velocity | en_US |
dc.subject | Mean velocity | en_US |
dc.subject | Peak systolic velocity | en_US |
dc.title | Normative Values of Cerebral Blood Flow Velocities in Very Low Birth Weight Neonates During First 28 Days of Life | en_US |
dc.type | Journal Article | en_US |
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