Study on early intervention with ACE inhibitor in myocardical infarction and short term outcome.

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dc.contributor.authorHazra, B Ren_US
dc.contributor.authorRoy, B Pen_US
dc.contributor.authorGuha, Sen_US
dc.contributor.authorRakshit, Ken_US
dc.contributor.authorGhosh, M Ben_US
dc.date.accessioned2001-09-23en_US
dc.date.accessioned2009-05-31T15:44:25Z
dc.date.available2001-09-23en_US
dc.date.available2009-05-31T15:44:25Z
dc.date.issued2001-09-23en_US
dc.description.abstractThe present study was carried out on 100 patients with acute myocardial infarction (AMI) being treated with angiotensin converting enzyme (ACE) inhibitor and another 80 patients with conventional treatment but without ACE inhibitor during the period from May 1, 1995 to August 7, 1996 in Medical College, Calcutta. Clinical and other laboratory investigations including echocardiographic parameters were noted and recorded meticulously within 24-48 hours after AMI and repeated at 4th week. The present study based on non-invasive methods other than haemodynamic methods has shown that the echocardiographic assessment of left ventricular functional parameters after 4 weeks of ACE inhibitor therapy (n = 100) were better in treated group in comparison to control group without ACE inhibitor (n = 80) and the difference was statistically significant at 99% level of confidence. Overall mortality was 4% in ACE inhibitor group and 8.75% in the control group. This short term study with early intervention with ACE inhibitor within 48 hours of AMI has shown statistically significant evidence of beneficial effect of ACE inhibitor in improving the ventricular functional parameters and also reducing short term mortality from cardiac cause within 4 weeks compared to the group not receiving ACE inhibitors.en_US
dc.description.affiliationDepartment of Medicine, Medical College, Calcutta.en_US
dc.identifier.citationHazra BR, Roy BP, Guha S, Rakshit K, Ghosh MB. Study on early intervention with ACE inhibitor in myocardical infarction and short term outcome. Journal of the Indian Medical Association. 2001 Sep; 99(9): 489-92en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/103746
dc.language.isoengen_US
dc.source.urihttps://www.jimaonline.org.in/en_US
dc.subject.meshAdulten_US
dc.subject.meshAgeden_US
dc.subject.meshAged, 80 and overen_US
dc.subject.meshAngiotensin-Converting Enzyme Inhibitors --therapeutic useen_US
dc.subject.meshCaptopril --therapeutic useen_US
dc.subject.meshFemaleen_US
dc.subject.meshHumansen_US
dc.subject.meshMaleen_US
dc.subject.meshMiddle Ageden_US
dc.subject.meshMyocardial Infarction --drug therapyen_US
dc.subject.meshTime Factorsen_US
dc.subject.meshTreatment Outcomeen_US
dc.subject.meshVentricular Function, Left --drug effectsen_US
dc.titleStudy on early intervention with ACE inhibitor in myocardical infarction and short term outcome.en_US
dc.typeJournal Articleen_US
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