Renal angiomyolipomas--a study of 18 cases.

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dc.contributor.authorKulkarni, Bijalen_US
dc.contributor.authorDesai, Sangeeta Ben_US
dc.contributor.authorDave, Brijalen_US
dc.contributor.authorTongaonkar, Hemant Ben_US
dc.contributor.authorKulkarni, Jagdish Nen_US
dc.contributor.authorChinoy, Roshni Fen_US
dc.date.accessioned2005-10-22en_US
dc.date.accessioned2009-05-29T11:35:09Z
dc.date.available2005-10-22en_US
dc.date.available2009-05-29T11:35:09Z
dc.date.issued2005-10-22en_US
dc.description.abstractAngiomyolipoma is a distinctive neoplasm composed of an intimate admixture of three components, viz. mature adipocytes, smooth muscle cells and blood vessels. This study was undertaken to better define the various morphological patterns of angiomyolipoma and their immunohistochemical profile. The paraffin blocks and slides of 18 cases of renal angiomyolipoma, accessioned over a period of 8 years from Tata Memorial Hospital, were reviewed. There were 2 men and 16 women in the age range of 17 to 68 years. Pre-operative fine needle aspiration cytology (FNAC) was performed in 6 cases, of which 5 were erroneously diagnosed as renal cell carcinomal sarcoma. Histologically, 14 cases revealed conventional histology. The remaining 4 cases were particularly misleading posing diagnostic problems due to variant patterns (leiomyomatous variant-3 cases and epithelioid variant- 1 case). Apart from the usual histology, necrosis, giant cells, and varying degrees of nuclear pleomorphism were present in three of the cases. Immunohistochemistry performed in 16 cases revealed immunoreactivity for HMB45 in all the 16 tumors (100%), estrogen receptor (ER) and progesterone receptor ((PR) in 2 cases (12.5%) and 6 cases (37.5%) respectively.en_US
dc.description.affiliationDepartment of Surgical Pathology, Tata Memorial Hospital, Mumbai.en_US
dc.identifier.citationKulkarni B, Desai SB, Dave B, Tongaonkar HB, Kulkarni JN, Chinoy RF. Renal angiomyolipomas--a study of 18 cases. Indian Journal of Pathology & Microbiology. 2005 Oct; 48(4): 459-63en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/73675
dc.language.isoengen_US
dc.source.urihttps://www.ijpmonline.orgen_US
dc.subject.meshAdolescenten_US
dc.subject.meshAdulten_US
dc.subject.meshAgeden_US
dc.subject.meshAngiomyolipoma --diagnosisen_US
dc.subject.meshAntigens, Neoplasmen_US
dc.subject.meshDiagnostic Errorsen_US
dc.subject.meshFemaleen_US
dc.subject.meshHumansen_US
dc.subject.meshImmunohistochemistryen_US
dc.subject.meshIndiaen_US
dc.subject.meshKidney Diseases --diagnosisen_US
dc.subject.meshMaleen_US
dc.subject.meshMiddle Ageden_US
dc.subject.meshNeoplasm Proteins --metabolismen_US
dc.titleRenal angiomyolipomas--a study of 18 cases.en_US
dc.typeJournal Articleen_US
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