Sodium stibogluconate and polymorphic ventricular tachycardia.
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2005-03-07
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Abstract
Numerous antimicrobials including pentavalent antimonials are implicated in causing prolong QT-interval and ventricular tachycardia. Torsades de pointes is rarely documented with use of sodium stibogluconate. Here is described a 12-yr-old girl with visceral leishmaniasis, who developed syncopal attacks, prolong QT-interval, polymorphic ventricular tachycardia and torsades de pointes after completing a course of Stibogluconate (20 mg/kg/day for 30 days). Prolong lidocaine infusion and cardioversion were life saving.
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Baranwal AK, Mandal RN, Singh R, Singhi SC. Sodium stibogluconate and polymorphic ventricular tachycardia. Indian Journal of Pediatrics. 2005 Mar; 72(3): 269