Serum Procalcitonin and CRP Level as Severity Marker of Dengue Fever : An Observational Study in Medical College, Kolkata
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Date
2025-01
Journal Title
Journal ISSN
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Publisher
Indian Medical Association
Abstract
Background : Among different markers of inflammation and sepsis, Procalcitonin (PCT) and C-reactive Protein (CRP) are being studied to investigate their accuracy for the diagnosis of bacterial infections. However, their role in viral diseases like Dengue is less explored. Aims and Objectives : To find relationship between serum Procalcitonin and CRP with severity of Dengue Fever. Materials and Methods : An Observational study conducted among 100 Dengue patients (IgM Positive) and were subjected to Tests for Serum Procalcitonin and CRP along with other routine blood tests, results were compared between three groups Dengue Fever (DF), Dengue Hemorrhagic Fever (DHF) and Dengue Shock Syndrome (DSS). Results : We found that mean CRP in DF, DHF, DSS are respectively 16.52, 42.59 and 77.20 and mean Procalcitonin in DF, DHF, DSS are respectively 0.0519, 0.2574 and 0.7800. Conclusion : We found that Abnormal CRP was more significant with DHF and DSS patients and Procalcitonin is more elevated in DSS, though abnormal Procalcitonin in DHF also statistically significant.
Description
Keywords
Dengue Fever, CRP, Procalcitonin.
Citation
Ghosh SK, Saha M, Pal S, Maji S, Mondal SS, Ghosh UC. Serum Procalcitonin and CRP Level as Severity Marker of Dengue Fever : An Observational Study in Medical College, Kolkata. Journal of The Indian Medical Association. 2025 Jan; 123(1): 39-43