High sensitive C-reactive protein: a novel biochemical markers and its role in coronary artery disease.

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dc.contributor.authorMitra, Ben_US
dc.contributor.authorPanja, Men_US
dc.date.accessioned2005-01-29en_US
dc.date.accessioned2009-05-30T19:30:56Z
dc.date.available2005-01-29en_US
dc.date.available2009-05-30T19:30:56Z
dc.date.issued2005-01-29en_US
dc.description51 references.en_US
dc.description.abstractA series of prospective studies provide consistent data documenting that mild elevation of baseline levels of hs-CRP among apparently healthy individuals is associated with higher long-term risk for future cardiovascular events. This predictive capacity of hs-CRP is independent of traditional cardiovascular risk factors and offers a prognostic advantage over measurement of lipid alone. PHS and CARE trial suggest that the increased risk associated with systemic inflammation may be modified with certain preventive therapies and that inflammatory marker specifically hs-CRP may help to identify those who would benefit most from these pharmacological intervention. hs-CRP is the novel and evolving biomarker which provides a most useful predictive indicator for subsequent cardiovascular events. Based on various studies, increased hs-CRP levels in patients with high risk cardiovascular disease without documented CAD warrant treatment with statin even if LDL-C levels are within target range. Patients with documented CAD and high hs-CRP levels should be followed, and there risk factors should be managed aggressively.en_US
dc.description.affiliationDepartment of Internal Medicine, Institute of Post Graduate Medical Education and Research, SSKM Hospital, Kolkata.en_US
dc.identifier.citationMitra B, Panja M. High sensitive C-reactive protein: a novel biochemical markers and its role in coronary artery disease. Journal of the Association of Physicians of India. 2005 Jan; 53(): 25-32en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/86846
dc.language.isoengen_US
dc.source.urihttps://www.japi.orgen_US
dc.subject.meshBiological Markers --blooden_US
dc.subject.meshC-Reactive Protein --analysisen_US
dc.subject.meshCoronary Artery Disease --blooden_US
dc.subject.meshHumansen_US
dc.subject.meshInflammation --blooden_US
dc.subject.meshPrognosisen_US
dc.subject.meshRisk Assessment --methodsen_US
dc.subject.meshRisk Factorsen_US
dc.titleHigh sensitive C-reactive protein: a novel biochemical markers and its role in coronary artery disease.en_US
dc.typeJournal Articleen_US
dc.typeReviewen_US
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