A comparative study to determine the role of pre and post-operative antibiotic therapy versus only pre-operative antibiotic therapy in patients of non-perforated acute appendicitis

dc.contributor.authorChowdegowda, Goutam K.en_US
dc.contributor.authorArya, Satya V.en_US
dc.contributor.authorSharma, Ashok K.en_US
dc.contributor.authorKalwaniya, Dheer Singhen_US
dc.contributor.authorBajwa, Jaspreet Singhen_US
dc.date.accessioned2020-11-18T10:05:38Z
dc.date.available2020-11-18T10:05:38Z
dc.date.issued2020-10
dc.description.abstractBackground: If properly used in appendicitis, antibiotics can reduce the rate of infection by 50%. The use of post-operative antibiotics for preventing infective complications in non-perforated cases is still controversial.Methods: A randomised prospective study was conducted in the Department of Surgery, Vardhman Mahavir Medical College and Safdarjung Hospital, New Delhi with patients who presented acute appendicitis. A minimum number of 30 patients each in group A (pre-operative and post-operative antibiotics) and group B (only pre-operative antibiotics) were evaluated for 18 months, from January 2018 to June 2019.Results: The mean age of group A is 29.9±15.16 years and in group B is 25.97±9.470 years (p value=0.122, insignificant). There was male preponderance. The seroma formation in both the groups was 10.00% and no patients developed intra-abdominal abscess. The incidence of local site oedema was 10% in both the groups A and B and their p value is insignificant. In both the groups A and B, 10% of the people developed pus discharge from the stitch line and the p value is insignificant. In group A, 6.67% of the patients and in group B 10.00% of the patients developed stitch line inflammatory changes and the p value insignificant. In group A, 13.3% and in group B, 10.00% of the patients developed fever and their p value is 1. The mean length of hospital in case 1.23±0.5 days (group A) and is 1.17±0.45 days (group B) (p value=0.508).Conclusions: Hence we can conclude that a well-chosen and adequately-timed pre-operative antibiotics are adequate in preventing post-operative complications and post-operative antibiotics do not affect the same.en_US
dc.identifier.affiliationsDepartment of General Surgery, VMMC and Safdarjung Hospital, New Delhi, Indiaen_US
dc.identifier.citationChowdegowda Goutam K., Arya Satya V., Sharma Ashok K., Kalwaniya Dheer Singh, Bajwa Jaspreet Singh. A comparative study to determine the role of pre and post-operative antibiotic therapy versus only pre-operative antibiotic therapy in patients of non-perforated acute appendicitis. International Surgery Journal. 2020 Oct; 7(10): 3305-3310en_US
dc.identifier.issn2349-3305
dc.identifier.issn2349-2902
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/213387
dc.languageenen_US
dc.publisherMedip Academyen_US
dc.relation.issuenumber10en_US
dc.relation.volume7en_US
dc.source.urihttps://dx.doi.org/10.18203/2349-2902.isj20204127en_US
dc.subjectAcute appendicitisen_US
dc.subjectSeromaen_US
dc.subjectSurgical site infectionsen_US
dc.titleA comparative study to determine the role of pre and post-operative antibiotic therapy versus only pre-operative antibiotic therapy in patients of non-perforated acute appendicitisen_US
dc.typeJournal Articleen_US
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