The efficacy of 5% topical tea tree oil gel in mild to moderate acne vulgaris: a randomized, double-blind placebo-controlled study.

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dc.contributor.authorEnshaieh, Shahlaen_US
dc.contributor.authorJooya, Abolfazlen_US
dc.contributor.authorSiadat, Amir Hosseinen_US
dc.contributor.authorIraji, Faribaen_US
dc.date.accessioned2009-05-28T08:49:54Z
dc.date.available2009-05-28T08:49:54Z
dc.date.issued2007-01-23en_US
dc.description.abstractBACKGROUND: Finding an effective treatment for acne that is well tolerated by the patients is a challenge. One study has suggested the efficacy of tea tree oil in treatment of the acne vulgaris. AIM: To determine the efficacy of tea tree oil in mild to moderate acne vulgaris. METHODS: This was a randomized double-blind clinical trial performed in 60 patients with mild to moderate acne vulgaris. They were randomly divided into two groups and were treated with tea tree oil gel (n=30) or placebo (n=30). They were followed every 15 days for a period of 45 days. Response to treatment was evaluated by the total acne lesions counting (TLC) and acne severity index (ASI). The data was analyzed statistically using t-test and by SPSS program. RESULTS: There were no significant differences regarding demographic characteristics between the two groups. There was a significant difference between tea tree oil gel and placebo in the improvement of the TLC and also regarding improvement of the ASI. In terms of TLC and ASI, tea tree oil gel was 3.55 times and 5.75 times more effective than placebo respectively. Side-effects with both groups were relatively similar and tolerable. CONCLUSION: Topical 5% tea tree oil is an effective treatment for mild to moderate acne vulgaris.en_US
dc.description.affiliationDepartment of Dermatology, Skin Diseases and Leishmaniasis Research Center, Isfahan University of Medical Sciences, Isfahan, Iran.en_US
dc.identifier.citationEnshaieh S, Jooya A, Siadat AH, Iraji F. The efficacy of 5% topical tea tree oil gel in mild to moderate acne vulgaris: a randomized, double-blind placebo-controlled study. Indian Journal of Dermatology, Venereology and Leprology. 2007 Jan-Feb; 73(1): 22-5en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/53188
dc.language.isoengen_US
dc.source.urihttps://www.ijdvl.comen_US
dc.subject.meshAcne Vulgaris --drug therapyen_US
dc.subject.meshAdministration, Topicalen_US
dc.subject.meshAdolescenten_US
dc.subject.meshAdulten_US
dc.subject.meshAnti-Infective Agents, Local --administration & dosageen_US
dc.subject.meshDouble-Blind Methoden_US
dc.subject.meshFemaleen_US
dc.subject.meshGelsen_US
dc.subject.meshHumansen_US
dc.subject.meshMaleen_US
dc.subject.meshSeverity of Illness Indexen_US
dc.subject.meshTea Tree Oil --administration & dosageen_US
dc.subject.meshTreatment Outcomeen_US
dc.titleThe efficacy of 5% topical tea tree oil gel in mild to moderate acne vulgaris: a randomized, double-blind placebo-controlled study.en_US
dc.typeJournal Articleen_US
dc.typeRandomized Controlled Trialen_US
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