Microsponge: An Innovative Strategy For Drug Delivery System

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dc.contributor.authorG., CHAITRAen_US
dc.contributor.authorB.A, SOWMYAen_US
dc.date.accessioned2020-09-24T07:33:48Z
dc.date.available2020-09-24T07:33:48Z
dc.date.issued2019-12
dc.description.abstractMicrosponge technology has been introduced in topical drug products to facilitatethe controlled release of active drug into the skin in order to reduce systemic exposure andminimize local cutaneous reactions to active drugs. Microsponge consists of macroporousbeads, typically 10-25ยต in diameter, loaded with active agent. When applied to the skin, themicrosponge releases its active ingredients on a time mode and also in response to otherstimuli. Microsponge drug delivery technology holds a great promise for reaching the goal ofcontrolled and site-specific drug delivery and hence, has attracted wide attention ofresearchers. This article presents a broad review of Microsponges delivery system discussingthe principles and preparation methods. Appropriate analytical techniques for characterizationof Microsponges like Particle size and its distribution, surface morphology, porosity, densityare covered. These microsponges are used in the sunscreens, creams, ointments, over-thecounter skin care preparations, which are meant for topical application. Microsponge drugdelivery can provide increased efficacy for topically active agents with enhanced safety,extended product stability and improved aesthetic properties in an efficient and novel manner.They are mostly used for topical use and have recently been used for oral administrationen_US
dc.identifier.affiliationsDepartment of Pharmaceutics, East West College of Pharmacy, Bangalore-91en_US
dc.identifier.affiliationsDepartment of Pharmacology, East West College of Pharmacy, Bangalore-91en_US
dc.identifier.citationG. Chaitra, B.A Sowmya. Microsponge: An Innovative Strategy For Drug Delivery Systemen_US
dc.identifier.citationCurrent Status And Future Prospects. International Journal of Pharmaceutical Research and Bioscience (IJPRBS). 2019 Dec; 8(6): 23-36en_US
dc.identifier.issn2277-8713
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/203800
dc.languageenen_US
dc.publisherBimonthly published online Journalen_US
dc.relation.issuenumber6en_US
dc.relation.volume8en_US
dc.source.urihttps://www.ijprbs.com/issuedocs/2019/12/IJPRBS%201488.pdfen_US
dc.subjectMicrospongeen_US
dc.subjectMDSen_US
dc.subjectcontrolled releaseen_US
dc.subjectTopical drug deliveryen_US
dc.subjectLiquid-Liquid Suspension Polymerizationen_US
dc.subjectQuasi emulsion method.en_US
dc.titleMicrosponge: An Innovative Strategy For Drug Delivery Systemen_US
dc.titleCurrent Status And Future Prospectsen_US
dc.typeJournal Articleen_US
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