Quantitative and qualitative assessment of evaporative dry eye post intense pulsed light therapy, a prospective study

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dc.contributor.authorPatwardhan, Sourabh Den_US
dc.contributor.authorSangle, Ankitaen_US
dc.contributor.authorPatwardhan, Nidhi Sen_US
dc.contributor.authorMane, Seemaen_US
dc.date.accessioned2025-06-19T05:52:06Z
dc.date.available2025-06-19T05:52:06Z
dc.date.issued2025-04
dc.description.abstractPurpose: This study aimed to determine the effect of intense pulsed light(IPL) treatment on meibomian gland disease. Settings and Design: This is a prospective interventional study. Methods: Seventy eyes of patients with dry eye disease undergoing three sessions of IPL therapy, 15 days apart, were included. Each patient completed the dry eye questionnaire (SPEED) for symptomatic assessment. Dry eye evaluation tests were performed, including Schirmer’s 1 test, meiboscopy, noninvasive tear break?up time (NIBUT) and interferometry. These tests were repeated before each IPL session. Statistical Analysis Used: Data analysis was performed using IBM SPSS Statistics software (Version 20, Inc., Chicago, Illinois, USA). To Kolmogorov–Smirnov test was used to assess the normality of the variables. The Chi?square test was applied for statistical analysis. Level of significance was set at p ? 0.05. Results: The mean symptom score from the dry eye questionnaire(SPEED) showed a significant reduction of 24.5% (p < 0.001) in symptoms. Schirmer’s 1 test showed an improvement of 16.43% on day 15 and 40.13% on day 45. Meiboscopy grade improved by 13.54% on day 45. NIBUT improved from 53.29% on day 15 to 135.53% on day 45. Interferometry showed an improvement of 58.91% on day 45.Conclusions: The various investigative tests demonstrated both qualitative and quantitative improvements in dry eye disease, and patients reported symptomatic relief. The effects of IPL therapy, in terms of symptomatic relief, continued to improve with each session. The quality of the tear film also improved progressively. IPL therapy is a potential therapeutic option for MGD.en_US
dc.identifier.affiliationsDepartment of Ophthalmology, Nandadeep Eye Hospital, Sangli, Maharashtra, Indiaen_US
dc.identifier.affiliationsDepartment of Ophthalmology, Nandadeep Eye Hospital, Sangli, Maharashtra, Indiaen_US
dc.identifier.affiliationsDepartment of Ophthalmology, Nandadeep Eye Hospital, Sangli, Maharashtra, Indiaen_US
dc.identifier.affiliationsDepartment of Ophthalmology, Nandadeep Eye Hospital, Sangli, Maharashtra, Indiaen_US
dc.identifier.citationPatwardhan Sourabh D, Sangle Ankita, Patwardhan Nidhi S, Mane Seema. Quantitative and qualitative assessment of evaporative dry eye post intense pulsed light therapy, a prospective study. Indian Journal of Ophthalmology. 2025 Apr; 73(4): 590-593en_US
dc.identifier.issn0301-4738
dc.identifier.issn1998-3689
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/249881
dc.languageenen_US
dc.publisherWolters Kluwer – Medknowen_US
dc.relation.issuenumber4en_US
dc.relation.volume73en_US
dc.source.urihttps://doi.org/10.4103/IJO.IJO_1136_24en_US
dc.subjectDry eye questionnaire ? SPEEDen_US
dc.subjectintense pulsed light therapyen_US
dc.subjectinterferometryen_US
dc.subjectmeibomian gland diseaseen_US
dc.subjectmeiboscopyen_US
dc.titleQuantitative and qualitative assessment of evaporative dry eye post intense pulsed light therapy, a prospective studyen_US
dc.typeJournal Articleen_US
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