Antimutagenic activity of plumbagin in Ames Salmonella typhimurium test.
| dc.contributor.author | Durga, R | en_US |
| dc.contributor.author | Sridhar, P | en_US |
| dc.contributor.author | Polasa, H | en_US |
| dc.date.accessioned | 1992-04-01 | en_US |
| dc.date.accessioned | 2009-05-27T07:24:05Z | |
| dc.date.available | 1992-04-01 | en_US |
| dc.date.available | 2009-05-27T07:24:05Z | |
| dc.date.issued | 1992-04-01 | en_US |
| dc.description.abstract | This paper reports the antimutagenic activity of plumbagin (5-hydroxy-2-methyl-1, 4-naphthoquinone) against certain known chemical mutagens in a standard mutagenicity test system of Ames using S. typhimurium strains. Plumbagin by itself did not show any mutagenic effect, whereas it reduced significantly the mutagenic effect of 4-nitrophenylene diammine, phenyl hydrazine and sodium azide in test strains of S. typhimurium, suggesting that plumbagin possessed antimutagenic activity. | en_US |
| dc.description.affiliation | Department of Microbiology, Osmania University, Hyderabad. | en_US |
| dc.identifier.citation | Durga R, Sridhar P, Polasa H. Antimutagenic activity of plumbagin in Ames Salmonella typhimurium test. Indian Journal of Medical Research. 1992 Apr; 96(): 143-5 | en_US |
| dc.identifier.uri | https://imsear.searo.who.int/handle/123456789/20554 | |
| dc.language.iso | eng | en_US |
| dc.source.uri | https://icmr.nic.in/ijmr/ijmr.htm | en_US |
| dc.subject.mesh | Azides --antagonists & inhibitors | en_US |
| dc.subject.mesh | Humans | en_US |
| dc.subject.mesh | Indicators and Reagents | en_US |
| dc.subject.mesh | Mutagenesis --drug effects | en_US |
| dc.subject.mesh | Mutagenicity Tests | en_US |
| dc.subject.mesh | Naphthoquinones --pharmacology | en_US |
| dc.subject.mesh | Phenylhydrazines --antagonists & inhibitors | en_US |
| dc.subject.mesh | Salmonella typhimurium | en_US |
| dc.subject.mesh | Sodium Azide | en_US |
| dc.title | Antimutagenic activity of plumbagin in Ames Salmonella typhimurium test. | en_US |
| dc.type | Journal Article | en_US |
| dc.type | Research Support, Non-U.S. Gov't | en_US |
Files
License bundle
1 - 1 of 1