Co-infection of scrub typhus and leptospirosis in patients with pyrexia of unknown origin in Longding district of Arunachal Pradesh in 2013.

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dc.contributor.authorBorkakoty, Biswajyoti
dc.contributor.authorJakharia, Aniruddha
dc.contributor.authorBiswas, Dipankar
dc.contributor.authorMahanta, Jagadish
dc.date.accessioned2016-08-10T05:04:48Z
dc.date.available2016-08-10T05:04:48Z
dc.date.issued2016-01
dc.description.abstractBackground: Scrub typhus and leptospirosis are bacterial zoonotic disease causing high morbidity and mortality. The seasonal outbreak of pyrexia is common in Arunachal Pradesh (AP); many times the disease remains undiagnosed. Objective: An outbreak of pyrexia of unknown origin (PUO) occurred in Longding district of Arunachal Pradesh in 2013, with 108 deaths, which was investigated to elucidate the cause of illness. Methodology: Blood samples from the affected region with acute pyrexia were collected, and screened for the malaria parasite, scrub typhus IgM and leptospira IgM. Results: Scrub typhus IgM was reactive in 97% (30/31), and 25% (8/31) cases were co-infected with leptospira. Incidentally, scrub typhus reactive (67%) and leptospira co-infection (62.7%) were higher in females. Record of previous 3 years (2011–2013) from Longding, Community Health Centre showed an increase in indoor pyrexia cases by 2-fold or more during October and November. Conclusion: The present study is the first report of co-infection of scrub typhus with leptospirosis from Northeast India. Medical officers in this region should take scrub typhus and leptospirosis in their differential diagnosis of patients with PUO for early diagnosis and effective treatment.en_US
dc.identifier.citationBorkakoty Biswajyoti, Jakharia Aniruddha, Biswas Dipankar, Mahanta Jagadish. Co-infection of scrub typhus and leptospirosis in patients with pyrexia of unknown origin in Longding district of Arunachal Pradesh in 2013. Indian Journal of Medical Microbiology. 2016 Jan-Mar; 34(1): 88-91.en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/176555
dc.language.isoenen_US
dc.source.urihttps://www.ijmm.org/article.asp?issn=0255-0857;year=2016;volume=34;issue=1;spage=88;epage=91;aulast=Borkakotyen_US
dc.subjectArunachal Pradeshen_US
dc.subjectco-infectionen_US
dc.subjectleptospirosisen_US
dc.subjectpyrexia of unknown originen_US
dc.subjectscrub typhusen_US
dc.titleCo-infection of scrub typhus and leptospirosis in patients with pyrexia of unknown origin in Longding district of Arunachal Pradesh in 2013.en_US
dc.typeArticleen_US
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