Single-photon emission computed tomography (SPECT) in childhood epilepsy.

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dc.contributor.authorGulati, Sen_US
dc.contributor.authorBal, C Sen_US
dc.contributor.authorKalra, Ven_US
dc.date.accessioned2000-01-29en_US
dc.date.accessioned2009-05-30T15:24:09Z
dc.date.available2000-01-29en_US
dc.date.available2009-05-30T15:24:09Z
dc.date.issued2000-01-29en_US
dc.description9 references.en_US
dc.description.abstractThe success of epilepsy surgery is determined strongly by the precise location of the epileptogenic focus. The information from clinical and electrophysiological data needs to be strengthened by functional neuroimaging techniques. Single photon emission computed tomography (SPECT) available locally has proved useful as a localising investigation. It evaluates the regional cerebral blood flow and the comparison between ictal and interictal blood flow on SPECT has proved to be a sensitive nuclear marker for the site of seizure onset. Many studies justify the utility of SPECT in localising lesions to possess greater precision than interictal scalp EEG or anatomic neuroimaging. SPECT is of definitive value in temporal lobe epilepsy. Its role in extratemporal lobe epilepsy is less clearly defined. It is useful in various other generalized & partial seizure disorders including epileptic syndromes and helps in differentiating pseudoseizures from true seizures. The need for newer radiopharmaceutical agents with specific neurochemical properties and longer shelf life are under investigation. Subtraction ictal SPECT co-registered to MRI is a promising new modality.en_US
dc.description.affiliationDepartment of Pediatrics, All India Institute of Medical Sciences, New Delhi.en_US
dc.identifier.citationGulati S, Bal CS, Kalra V. Single-photon emission computed tomography (SPECT) in childhood epilepsy. Indian Journal of Pediatrics. 2000 Jan; 67(1 Suppl): S32-9en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/83587
dc.language.isoengen_US
dc.source.urihttps://medind.nic.in/icb/icbai.shtmlen_US
dc.subject.meshBrain --blood supplyen_US
dc.subject.meshChilden_US
dc.subject.meshEpilepsy --classificationen_US
dc.subject.meshFemaleen_US
dc.subject.meshForecastingen_US
dc.subject.meshHumansen_US
dc.subject.meshInfanten_US
dc.subject.meshMaleen_US
dc.subject.meshPredictive Value of Testsen_US
dc.subject.meshSensitivity and Specificityen_US
dc.subject.meshTomography, Emission-Computed, Single-Photon --methodsen_US
dc.titleSingle-photon emission computed tomography (SPECT) in childhood epilepsy.en_US
dc.typeJournal Articleen_US
dc.typeReviewen_US
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