Prevalence of gestational diabetes mellitus (GDM) in women screened by glucose challenge test (GCT) at Maharaj Nakorn Chiang Mai Hospital.

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dc.contributor.authorChanprapaph, Pharuhasen_US
dc.contributor.authorSutjarit, Chatdaoen_US
dc.date.accessioned2009-05-27T18:02:25Z
dc.date.available2009-05-27T18:02:25Z
dc.date.issued2004-10-25en_US
dc.descriptionChotmaihet Thangphaet.en_US
dc.description.abstractOBJECTIVE: To assess the prevalence of GDM in GCT screened women at Maharaj Nakorn Chiang Mai Hospital. STUDY DESIGN: Retrospective descriptive study. SETTING: Department of Obstetric and Gynecology, Maharaj Nakorn Chiang Mai Hospital. MATERIAL AND METHOD: One thousand pregnant women who attended the antenatal care clinic and delivered at Maharaj Nakorn Chiang Mai Hospital from October 2001 to December 2002 were recruited into the study. Glucose challenge test (GCT), 50-g glucose oral load with 1-hr plasma glucose measurement, was performed in GDM high-risk pregnancies. If GCT was positive, oral glucose tolerance test (OGTT), 100-g glucose orally, was done to confirm the final diagnosis. All relevant data including demographic information, previous obstetric history, risk factors for GDM, GCT and OGTT results and pregnancy outcomes were collected for further statistical analysis. MAIN OUTCOME MEASUREs: Prevalence of GDM in GCT screened women, obstetric complications and pregnancy outcomes. RESULTS: There were totally 1000 pregnancies enrolled into the study. Despite 451 pregnant women being eligible for GCT only 411 cases were tested with 164 positive results. 29 cases of GDM were detected with the prevalence of 7.05%. (CI 95% = 0.048, 0.099). As a result, the sensitivity, specificity, positive predictive value, and negative predictive value of GCT were 100%, 64.66%, 17.68% and 0%, respectively. In the GDM group, the common indications for GCT screening were advanced maternal age (75.4%), familial diabetic history (22.1%) and glycosuria (6.8%). Furthermore, only I case of pregnancy-induced hypertension was found with cesarean section, preterm birth, LGA and SGA of 27. 6%, 10.3%, 3.45% and 13.79%, respectively. There were 2 cases of pregestational diabetes mellitus (PGD; 0.2%) with 40 high-risk pregnancies (4%) without screening. CONCLUSION: The selective GCT screening strategy was highly effective and revealed 7.05% of GDM prevalence. Its impact on obstetric complication and pregnancy outcome was inconclusive due to the small number of studied population. Careful history reviewing plays an important role in identifying GDM risk factor for GCT screening.en_US
dc.description.affiliationDepartment of Obstetrics and Gynecology, Faculty of Medicine, Chiang Mai University, Chiang Mai 50200, Thailand. pchanpra@mail.med.cmu.ac.then_US
dc.identifier.citationChanprapaph P, Sutjarit C. Prevalence of gestational diabetes mellitus (GDM) in women screened by glucose challenge test (GCT) at Maharaj Nakorn Chiang Mai Hospital. Journal of the Medical Association of Thailand. 2004 Oct; 87(10): 1141-6en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/38329
dc.language.isoengen_US
dc.source.urihttps://www.mat.or.th/journal/all.phpen_US
dc.subject.meshAdulten_US
dc.subject.meshDiabetes, Gestational --diagnosisen_US
dc.subject.meshFemaleen_US
dc.subject.meshGlucose Tolerance Testen_US
dc.subject.meshHospitals, Universityen_US
dc.subject.meshHumansen_US
dc.subject.meshPregnancyen_US
dc.subject.meshPregnancy Outcomeen_US
dc.subject.meshPrevalenceen_US
dc.subject.meshRetrospective Studiesen_US
dc.subject.meshRisk Factorsen_US
dc.subject.meshThailanden_US
dc.titlePrevalence of gestational diabetes mellitus (GDM) in women screened by glucose challenge test (GCT) at Maharaj Nakorn Chiang Mai Hospital.en_US
dc.typeJournal Articleen_US
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