Histomorphological study of salivary gland neoplasms: fifteen year study

Simple item page
dc.contributor.authorHemalata, M.en_US
dc.contributor.authorManjula, C. P.en_US
dc.contributor.authorNandi, Rishithaen_US
dc.date.accessioned2020-11-18T10:02:08Z
dc.date.available2020-11-18T10:02:08Z
dc.date.issued2020-07
dc.description.abstractBackground: The neoplasms of salivary glands are relatively uncommon and represent less than 2% of all human tumors. They are morphologically diverse, with marked heterogeneity among the different subtypes and even within the same tumor. The unpredictability in the long term outcome imposes a significant challenge in the clinical management.Methods: This is a descriptive study done in a tertiary care teaching hospital over a period of 15 years. Patient details were collected from medical case records. All specimens were evaluated for site, laterality, size, nature of the cut surface and intactness of the capsule. Two to 5 representative bits were taken from each specimen and subjected to routine fixation, processing and section cutting followed by Haematoxylin and Eosin staining.Results: A total of 138 salivary gland tumors were diagnosed from patients in the age group of 13 to 90 years with a mean age of 41.8 years. There were 53 (38.4%) males and 85 (61.6%) females with male to female ratio of 1:1.42. There were 115 (83.3%) benign tumors and 23 (16.7%) malignant tumors. Pleomorphic adenoma accounted for 70.3% of all salivary gland tumors followed by mucoepidermoid carcinoma (10.9%), Warthin tumor (8%), basal cell adenoma (2.9%), adenoid cystic carcinoma (2.2%), squamous cell carcinoma (2.2%), myoepithelioma (1.4%), oxyphillic adenoma (0.7%), acinic cell carcinoma (0.7%) and salivary duct carcinoma (0.7%).Conclusions: The salivary gland neoplasms are relatively uncommon head and neck tumors. Parotid gland is the commonest site of occurrence. Pleomorphic adenoma is the commonest benign and mucoepidermoid carcinoma the commonest malignant salivary gland tumor.en_US
dc.identifier.affiliationsDepartment of Pathology, Kempegowda Institute of Medical Sciences, Bengaluru, Karnataka, Indiaen_US
dc.identifier.citationHemalata M., Manjula C. P., Nandi Rishitha. Histomorphological study of salivary gland neoplasms: fifteen year study. International Journal of Research in Medical Sciences. 2020 Jul; 8(7): 2469-2476en_US
dc.identifier.issn2320-6071
dc.identifier.issn2320-6012
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/212444
dc.languageenen_US
dc.publisherMedip Academyen_US
dc.relation.issuenumber7en_US
dc.relation.volume8en_US
dc.source.urihttps://dx.doi.org/10.18203/2320-6012.ijrms20202881en_US
dc.subjectMucoepidermoid tumoren_US
dc.subjectPleomorphic adenomaen_US
dc.subjectSalivary gland tumorsen_US
dc.titleHistomorphological study of salivary gland neoplasms: fifteen year studyen_US
dc.typeJournal Articleen_US
Files
Original bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
ijrms2020v8n7p2469.pdf
Size:
1.16 MB
Format:
Adobe Portable Document Format
Download
Collections
International Journal of Research in Medical Sciences