Outcome in West syndrome.

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dc.contributor.authorSharma, Natwar Lalen_US
dc.contributor.authorVishwanthan, Venkataramanen_US
dc.date.accessioned2008-07-13en_US
dc.date.accessioned2009-05-27T05:13:04Z
dc.date.available2008-07-13en_US
dc.date.available2009-05-27T05:13:04Z
dc.date.issued2008-07-13en_US
dc.description.abstractOBJECTIVES: To assess the seizure and developmental outcome in children with West syndrome with respect to treatment lag. METHODS: Twenty-six children satisfying inclusion criteria of West syndrome i.e., infantile spasms, psychomotor retardation and abnormal EEG pattern were prospectively evaluated. Response to treatment was assessed based on seizure control, EEG, developmental assessment and parental observations. RESUltS: The time lag from onset of seizures to appropriate treatment was <1 month in 11 children; 1-6 months in 8 children; and >6 months in 7 children. Children with treatment lag <1 month fared better than those who had a large treatment lag (P<0.05). Children with good seizure control also showed better developmental improvement (P<0.05). CONCLUSION: Children with West syndrome have better seizure control and development, if the treatment is started within 1 month of onset of symptoms.en_US
dc.description.affiliationDepartment of Pediatric Neurology, Kanchi Kamakoti CHILDS Trust Hospital, Chennai, India. drnutties2000@yahoo.co.inen_US
dc.identifier.citationSharma NL, Vishwanthan V. Outcome in West syndrome. Indian Pediatrics. 2008 Jul; 45(7): 559-63en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/9195
dc.language.isoengen_US
dc.source.urihttps://indianpediatrics.neten_US
dc.subject.meshAdrenocorticotropic Hormone --therapeutic useen_US
dc.subject.meshAnticonvulsants --therapeutic useen_US
dc.subject.meshBrain --physiopathologyen_US
dc.subject.meshChild, Preschoolen_US
dc.subject.meshCognition Disorders --diagnosisen_US
dc.subject.meshElectroencephalographyen_US
dc.subject.meshFemaleen_US
dc.subject.meshHumansen_US
dc.subject.meshInfanten_US
dc.subject.meshMaleen_US
dc.subject.meshNeuropsychological Testsen_US
dc.subject.meshProspective Studiesen_US
dc.subject.meshSeverity of Illness Indexen_US
dc.subject.meshSpasms, Infantile --complicationsen_US
dc.subject.meshValproic Acid --therapeutic useen_US
dc.titleOutcome in West syndrome.en_US
dc.typeJournal Articleen_US
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