Syndrome of inappropriate secretion of antidiuretic hormone associated with strongyloidiasis.

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dc.contributor.authorHayashi, Eijien_US
dc.contributor.authorOhta, Nobuoen_US
dc.contributor.authorYamamoto, Hiroshien_US
dc.date.accessioned2009-05-27T16:13:46Z
dc.date.available2009-05-27T16:13:46Z
dc.date.issued2007-03-02en_US
dc.descriptionThe Southeast Asian Journal of Tropical Medicine and Public Health.en_US
dc.description.abstractWe report a case of syndrome of inappropriate secretion of antidiuretic hormone (SIADH) with accompanying severe strongyloidiasis in a 52-year-old male. On admission, he showed drowsiness and emaciation with severe hyponatremia. We gave sodium (saline or salts) in an i.v. drip infusion and orally without improvement. A urinalysis and plasma osmotic pressure test indicated SIADH, therefore, treatment was changed to restrict his sodium intake. The hyponatremia gradually improved initially, but the appetite loss, nausea, and hyponatremia continued. Endoscopy revealed white patches on the stomach wall and histopathological examination revealed infestation of the mucosal epithelium with numerous Strongyloides stercoralis larvae. Ivermectin treatment was then initiated and the abdominal symptoms and hyponatremia gradually resolved. We carefully investigated the underlying cause of the SIADH, such as disease of the central nervous system, lung cancer, and other malignancies, but no abnormality or clear cause could be found. We concluded that the patient developed SIADH secondary to severe S. stercoralis infection.en_US
dc.description.affiliationSection of Environmental Parasitology, Department of International Health Development, Division of Public Health, Graduate School, Tokyo Medical and Dental University, 1-5-45 Yushima, Bunkyo-ku, Tokyo 113-8519, Japan. ehamzoo@pref-hosp.togane.chiba.jpen_US
dc.identifier.citationHayashi E, Ohta N, Yamamoto H. Syndrome of inappropriate secretion of antidiuretic hormone associated with strongyloidiasis. The Southeast Asian Journal of Tropical Medicine and Public Health. 2007 Mar; 38(2): 239-46en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/34724
dc.language.isoengen_US
dc.source.urihttps://www.tm.mahidol.ac.th/seameo/2007_38_2/05-3927.pdfen_US
dc.subject.meshAnimalsen_US
dc.subject.meshAntiparasitic Agents --administration & dosageen_US
dc.subject.meshArginine Vasopressin --secretionen_US
dc.subject.meshHumansen_US
dc.subject.meshHyponatremia --etiologyen_US
dc.subject.meshInappropriate ADH Syndrome --etiologyen_US
dc.subject.meshIntestinal Diseases, Parasitic --complicationsen_US
dc.subject.meshIvermectin --administration & dosageen_US
dc.subject.meshJapanen_US
dc.subject.meshMaleen_US
dc.subject.meshMiddle Ageden_US
dc.subject.meshSaline Solution, Hypertonic --administration & dosageen_US
dc.subject.meshStrongyloides stercoralis --isolation & purificationen_US
dc.subject.meshStrongyloidiasis --complicationsen_US
dc.subject.meshTreatment Outcomeen_US
dc.titleSyndrome of inappropriate secretion of antidiuretic hormone associated with strongyloidiasis.en_US
dc.typeCase Reportsen_US
dc.typeJournal Articleen_US
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