Necrotizing ileitis caused by cytomegalovirus in patient with systemic lupus erythematosus: case report.

Simple item page
dc.contributor.authorVilaichone, R Ken_US
dc.contributor.authorMahachai, Ven_US
dc.contributor.authorEiam-Ong, Sen_US
dc.contributor.authorKullavanuaya, Pen_US
dc.contributor.authorWisedopas, Nen_US
dc.contributor.authorBhattarakosol, Pen_US
dc.date.accessioned2009-05-27T20:08:19Z
dc.date.available2009-05-27T20:08:19Z
dc.date.issued2001-06-01en_US
dc.descriptionChotmaihet Thangphaet.en_US
dc.description.abstractWe report a systemic lupus erythematosus (SLE) patient with necrotizing ileitis diagnosed at a tertially care centre in Thailand. The patient was surgically explored because peritonitis was suspected and segmental gangrenous and perforation of the terminal iliem were found. The pathological finding was necrotizing ileitis with appearance of cytomegalic intranuclear inclusion body. The presence of cytomegalovirus (CMV) infection in tissue was confirmed by CMV-DNA detection using polymerase chain reaction and ELISA probe hybridization method. The hemoculture and peritoneal fluid culture results revealed no pathogenic organisms. Postoperatively, the clinical course of the patient deteriorated and she developed hypotension. Vasopressive drugs were administered without clinical improvement. She expired on day 5 postoperation. Regarding CMV infection, the organism involves the small bowel in only 4.3 per cent of all CMV infections of the gastrointestinal tract. Isolated cases of ileal perforation due to CMV infection have never been reported in a SLE patient. Thus, chronic right lower abdominal pain, fever with or without diarrhea in immunocompromised patients should cause clinicians to consider CMV ileitis in the differential diagnosis. Immediate surgical resection and prompt antiviral therapy lead to successful treatment.en_US
dc.description.affiliationDepartment of Medicine, Faculty of Medicine, Chulalongkom University, Bangkok, Thailand.en_US
dc.identifier.citationVilaichone RK, Mahachai V, Eiam-Ong S, Kullavanuaya P, Wisedopas N, Bhattarakosol P. Necrotizing ileitis caused by cytomegalovirus in patient with systemic lupus erythematosus: case report. Journal of the Medical Association of Thailand. 2001 Jun; 84 Suppl 1(): S469-73en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/42442
dc.language.isoengen_US
dc.source.urihttps://www.mat.or.th/journal/all.phpen_US
dc.subject.meshCytomegalovirus --isolation & purificationen_US
dc.subject.meshCytomegalovirus Infections --complicationsen_US
dc.subject.meshDNA, Viral --analysisen_US
dc.subject.meshEnzyme-Linked Immunosorbent Assayen_US
dc.subject.meshFatal Outcomeen_US
dc.subject.meshFemaleen_US
dc.subject.meshHumansen_US
dc.subject.meshIleitis --complicationsen_US
dc.subject.meshLupus Erythematosus, Systemic --complicationsen_US
dc.subject.meshMiddle Ageden_US
dc.subject.meshNecrosisen_US
dc.subject.meshPolymerase Chain Reactionen_US
dc.titleNecrotizing ileitis caused by cytomegalovirus in patient with systemic lupus erythematosus: case report.en_US
dc.typeCase Reportsen_US
dc.typeJournal Articleen_US
Files
License bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
license.txt
Size:
1.79 KB
Format:
Plain Text
Description:
Download
Collections
Journal of the Medical Association of Thailand