Comparison of Analgesic Effects of Levobupivacaine (0.25%) versus Bupivacaine (0.25%) using Ultrasound Guided Transversus Abdominis Plane Block in Total Abdominal Hysterectomy under General Anesthesia — An Interventional Study

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dc.contributor.authorDe, Susmitaen_US
dc.contributor.authorSur, Debajyotien_US
dc.contributor.authorRoy, Sankaren_US
dc.contributor.authorBhattacharya, Dipasrien_US
dc.date.accessioned2023-06-17T08:32:51Z
dc.date.available2023-06-17T08:32:51Z
dc.date.issued2022-02
dc.description.abstractBackground : Transversus Abdominis Plane (TAP) block is recently being used for effective pain relief following Total Abdominal Hysterectomy (TAH). Ultrasound guided block helps in correct localization of the plane and proper deposition of drugs. This study was done to compare the efficacy of Levobupivacaine and Bupivacaine in TAP block in TAH. Materials and Method : Seventy patients (ASA 1 and 2) prepared for TAH under General Anesthesia were randomly allocated into two groups. Ultrasound guided TAP block was performed bilaterally with 20ml of Levobupivacaine (0.25%) in Group A (n=35) and Bupivacaine (0.25%) in Group B (n=35) on each side of abdomen after skin closure at the end of operation. Intensity of pain was evaluated by 10cm Visual Analogue Scale (VAS) score at 0, 2, 6, 12,24 hours. If VAS >3, 1gram paracetamol infusion was given as rescue analgesic. Duration of analgesia, total rescue analgesic requirement and hemodynamic changes by measuring MAP and PR were noted. Results : VAS at 12 hours was significantly lower in Group A (mean 3.2±1) than Group B (mean 4.1±0.7, p<0.0001). Time of first rescue analgesic requirement was longer in Group A (mean 12.0±1.1h) compared to Group B (mean 11.2±1.1h, p=0.0059). Total analgesic requirement( paracetamol) in 24 hours was lower in Group A (mean 1.7±0.7g) compared to Group B (mean 2.2±0.7g, p=0.007). Hemodynamic changes were comparable in both groups. Conclusion : Levobupivacaine provided better postoperative analgesia than Bupivacaine with stable hemodynamic condition in TAP block.en_US
dc.identifier.affiliationsDepartment of Anaesthesiology, RG Kar Medical College, Kolkata 700004en_US
dc.identifier.affiliationsMBBS, 2nd year Postgraduate Traineeen_US
dc.identifier.affiliationsMD, Assistant Professoren_US
dc.identifier.affiliationsMD, Associate Professoren_US
dc.identifier.affiliationsMD, MNAMS, FIAPM, Professor and Head and Corresponding Authoren_US
dc.identifier.citationDe Susmita, Sur Debajyoti, Roy Sankar, Bhattacharya Dipasri . Comparison of Analgesic Effects of Levobupivacaine (0.25%) versus Bupivacaine (0.25%) using Ultrasound Guided Transversus Abdominis Plane Block in Total Abdominal Hysterectomy under General Anesthesia — An Interventional Study. Journal of The Indian Medical Association. 2022 Feb; 120(2): 37-41en_US
dc.identifier.issn0019-5847
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/216493
dc.languageenen_US
dc.publisherIndian Medical Associationen_US
dc.relation.issuenumber2en_US
dc.relation.volume120en_US
dc.source.urihttps://www.onlinejima.com/read_journals.php?article=875en_US
dc.subjectTAP blocken_US
dc.subjectLevobupivacaineen_US
dc.subjectBupivacaineen_US
dc.subjectPostoperative analgesiaen_US
dc.titleComparison of Analgesic Effects of Levobupivacaine (0.25%) versus Bupivacaine (0.25%) using Ultrasound Guided Transversus Abdominis Plane Block in Total Abdominal Hysterectomy under General Anesthesia — An Interventional Studyen_US
dc.typeJournal Articleen_US
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