Role of Measurement of Reactive Oxygen Species in Semen Sample of Patients with Male Factor Infertility and Treatment with Antioxidants in Patients with High ROS Levels

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dc.contributor.authorChatterjee, Satyabratoen_US
dc.contributor.authorTalwar, Pankajen_US
dc.date.accessioned2020-09-24T07:09:00Z
dc.date.available2020-09-24T07:09:00Z
dc.date.issued2019-02
dc.description.abstractIntroduction: It is a known fact that human sperms, producereactive oxygen species in small amounts, which is usefulfor normal functioning of the sperm mainly sperm oocyteinteraction acrosome reaction and capacitation. Recentresearch has shown that this ROS in increased amounts is acause of male infertility.Material and methods: It is a prospective control trial todetermine the abnormal pattern of reactive oxygen speciesin semen sample of patients with male factor infertility andto determine the effects of antioxidants in semen sampleof patients with high ROS in semen sample. 150 patientswere selected who were undergoing IVF treatment. Patientswere divided into three groups according to the severity ofabnormality in the semen analysis. The ROS levels of all thepatients were measured and compared with 50 normal fertiledonors. The patients whose ROS levels was found to be highwere then given antioxidants for 2 months and their ROSlevels in semen measured for improvement.Results: The ROS levels were significantly high in all thethree groups compared to fertile donors. The patients withhigh R0S levels were then treated with antioxidants and it wasseen that all the three groups had significant improvement intheir ROS levels.Conclusion: So, to conclude it is hence proved by my studythat ROS level measurement is useful for patients with malefactor infertility and the use of antioxidants significantly helpsin reducing ROS levels in semen.en_US
dc.identifier.affiliationsDepartment of ART, Army Hospital (R&R), New Delhien_US
dc.identifier.affiliationsProfessor (HOD ART), Department of ART, Army Hospital (R&R), New Delhi, Indiaen_US
dc.identifier.citationChatterjee Satyabrato, Talwar Pankaj. Role of Measurement of Reactive Oxygen Species in Semen Sample of Patients with Male Factor Infertility and Treatment with Antioxidants in Patients with High ROS Levels. International Journal of Contemporary Medical Research . 2019 Feb; 6(2): b1-b5en_US
dc.identifier.issn2393-915X
dc.identifier.issn2454-7379
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/202187
dc.languageenen_US
dc.publisherInternational Society for Contemporary Medical Researchen_US
dc.relation.issuenumber2en_US
dc.relation.volume6en_US
dc.source.urihttps://dx.doi.org//10.21276/ijcmr.2019.6.2.30en_US
dc.subjectMale Factor Infertilityen_US
dc.subjectROS Levelsen_US
dc.subjectAntioxidantsen_US
dc.titleRole of Measurement of Reactive Oxygen Species in Semen Sample of Patients with Male Factor Infertility and Treatment with Antioxidants in Patients with High ROS Levelsen_US
dc.typeJournal Articleen_US
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