An unlimited scope for novel formulations as orally disintegrating systems: Present and future prospects.
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Date
2011-03
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Abstract
An orally disintegrating tablet or orodispersible tablet (ODT) is a drug dosage form available for a
limited amount of over-the-counter (OTC) and prescription medications. ODTs differ from
traditional tablets in that they are designed to be dissolved on the tongue rather than swallowed
whole. The ODT serves as an alternative dosage form for patients who experience dysphasia
(difficulty in swallowing) or for where compliance is a known issue and therefore an easier dosage
form to take ensures that medication is taken. Common among all age groups, dysphasia is
observed in about 35% of the general population, as well as up to 60% of the elderly
institutionalized population and 18-22% of all patients in long-term care facilities. During the last
decade, ODTs have become available in a variety of therapeutic markets, both OTC and by
prescription. An additional reason to use ODTs is the convenience of a tablet that can be taken
without water.
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Keywords
ODT, Disintegration, Dissolution test, Oral dispersible tablets
Citation
Thakur Reeta Rani, Kashi Mridul. An unlimited scope for novel formulations as orally disintegrating systems: Present and future prospects. Journal of Applied Pharmaceutical Science. 2011 Mar; 1(1): 13-19.