Antihyperglycemic studies with boiled and non-boiled Vigna mungo seeds.

dc.contributor.authorMou, Shakila Jahan
dc.contributor.authorAhmed, Md Rasel
dc.contributor.authorRahman, Shahnaz
dc.contributor.authorBashar, ABM Anwarul
dc.contributor.authorIslam, Erena
dc.contributor.authorRahmatullah, Mohammed
dc.date.accessioned2016-09-01T09:44:10Z
dc.date.available2016-09-01T09:44:10Z
dc.date.issued2015-12
dc.description.abstractVigna mungo is a common leguminous crop cultivated in Bangladesh for its edible seeds, which are consumed following boiling or cooking. Since many lentil plants are known to have antihyperglycemic activity, it was of interest to determine the antihyperglycemic potential of seeds of V. mungo both in its boiled and non-boiled form. In oral glucose tolerance tests conducted in glucose-loaded Swiss albino mice, crude methanol extract of non-boiled seeds reduced blood glucose levels by 29.1, 36.5, 42.6, and 48.9%, respectively, at doses of 50, 100, 200, and 400 mg per kg body weight. At the afore-mentioned four doses, the percent reductions in blood glucose levels were, respectively, 24.1, 35.1, 39.4, and 46.5% with crude methanol extract of boiled seeds. Glibenclamide, a standard antihyperglycemic drug was observed to reduce blood glucose levels by 48.2%, when administered at a dose of 10 mg per kg. Thus the extracts of both non-boiled and boiled seeds demonstrated good antihyperglycemic potential comparable to glibenclamide and can be used as a readily available alternative to alleviate high blood glucose levels in diabetic patients.en_US
dc.identifier.citationMou Shakila Jahan, Ahmed Md Rasel, Rahman Shahnaz, Bashar ABM Anwarul, Islam Erena, Rahmatullah Mohammed. Antihyperglycemic studies with boiled and non-boiled Vigna mungo seeds. Journal of Applied Pharmaceutical Science. 2015 Dec; 5(12): 135-137.en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/176870
dc.language.isoenen_US
dc.source.urihttps://www.japsonline.com/abstract.php?article_id=1733en_US
dc.subjectVigna mungoen_US
dc.subjectantihyperglycemicen_US
dc.subjectFabaceaeen_US
dc.subjectlegumeen_US
dc.titleAntihyperglycemic studies with boiled and non-boiled Vigna mungo seeds.en_US
dc.typeArticleen_US
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